Record ID | marc_columbia/Columbia-extract-20221130-009.mrc:58509151:3446 |
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LEADER: 03446fam a2200409 a 4500
001 4051958
005 20221027024815.0
008 960125s1996 sz a b 001 0 eng c
010 $a 96004610
020 $a3805562543 (hardcover : alk. paper)
035 $a(OCoLC)34191090
035 $a(OCoLC)ocm34191090
035 $9ALQ6672HS
035 $a(NNC)4051958
035 $a4051958
040 $aDNLM/DLC$cDLC$dDLC$dOrLoB-B
050 00 $aRC280.P5$bO53 1996
060 10 $aW1 FR946F v.20 1996$aWK 585 O58 1996
082 00 $a616.99/447$220
245 00 $aOncogenesis and molecular biology of pituitary tumors /$cvolume editor, Shlomo Melmed.
260 $aBasel ;$aNew York :$bKarger,$c1996.
300 $a198 pages :$billustrations ;$c25 cm.
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
490 1 $aFrontiers of hormone research ;$vvol. 20
504 $aIncludes bibliographical references and index.
505 00 $tPreface /$rS. Melmed --$tFunctional Microanatomy of the Hypophysial-Pituitary Axis /$rR. M. Lechan --$tPit-1 in Pituitary Tumors /$rI. Pellegrini and P. Jacquet --$tExperimental and Clinical Models of CRH-Induced Pituitary Tumors /$rM. Karl and G. P. Chrousos --$tExperimental and Clinical Models of GHRH-Induced Pituitary Tumors /$rL. A. Frohman --$tRole on GnRH Receptors in the Pathogenesis of Pituitary Tumors /$rJ. M. Alexander and A. Klibanski --$tSomatostatin Receptor Subtypes in Pituitary Tumors /$rY. Greenman and S. Melmed --$tG-Protein Dysfunction in Pituitary Tumors /$rA. Spada and G. Faglia --$tOncogenes and Tumors Suppressor Genes in Pituitary Tumorigenesis /$rL. Pei and S. Melmed --$tRole of Parathyroid Hormone-Related Peptide in the Pathogenesis of Pituitary Adenomas /$rS. Yamashita, K. Akino and A. Ohtsuru --$tRole of TGF[alpha] in Pituitary Tumorigenesis /$rJ. McAndrew and J. E. Kudlow --$tRole of Chromosome II in Hereditary and Sporadic Pituitary Tumourigenesis /$rR. V. Thakker.
520 $aThis comprehensive volume focuses on mechanisms leading to pituitary tumor formation and progression. The individual chapters provide timely updates on developments in the rapidly expanding field of pituitary tumor pathogenesis.
520 8 $aResearchers from leading centers describe the fundamental functional anatomy of the pituitary, the structure and function of the hypothalamic hormone receptors as they relate to human pituitary adenomas, as well as disordered transcription factors, growth factors and signaling proteins in pituitary tumorigenesis. They also present transgenic models of pituitary tumor formation and report on chromosomal deletions observed in both hereditary and sporadic adenomas.
520 8 $a. The book is an essential and timely resource for basic and clinical endocrinologists, neurosurgeons and neuro-oncologists as it provides a state-of-the-art summary of our current understanding of the pathogenesis of these common tumors.
650 0 $aPituitary gland$xTumors$xMolecular aspects.
650 0 $aCarcinogenesis.$0http://id.loc.gov/authorities/subjects/sh85020155
650 12 $aPituitary Neoplasms$xgenetics.$0https://id.nlm.nih.gov/mesh/D010911Q000235
650 22 $aOncogenes.$0https://id.nlm.nih.gov/mesh/D009857
700 1 $aMelmed, Shlomo.$0http://id.loc.gov/authorities/names/n86128740
830 0 $aFrontiers of hormone research ;$vv. 20.$0http://id.loc.gov/authorities/names/n42011823
852 80 $boff,hsr$hserial$iF