| Record ID | marc_columbia/Columbia-extract-20221130-009.mrc:70310449:2691 |
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LEADER: 02691fam a2200433 a 4500
001 4057437
005 20221027025503.0
008 971202s1998 nyua b 001 0 eng
010 $a 97046769
020 $z05216204146 (hardcover)
020 $z05216297136 (pbk.)
035 $a(OCoLC)474871876
035 $a(OCoLC)ocn474871876
035 $9ANJ6892HS
035 $a(NNC)4057437
035 $a4057437
040 $aDLC$cDLC$dNNC-M$dOrLoB-B
050 00 $aQP620$b.B576 1998
082 00 $a572.8/633$221
245 00 $aBiological sequence analysis :$bprobalistic models of proteins and nucleic acids /$cRichard Durbin [and others].
260 $aCambridge, UK ;$aNew York :$bCambridge University Press,$c1998.
300 $axi, 356 pages :$billustrations ;$c26 cm
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
504 $aIncludes bibliographical references and index.
505 00 $g1.$tIntroduction --$g2.$tPairwise alignment --$g3.$tMarkov chains and hidden Markov models --$g4.$tPairwise alignment using HMMs --$g5.$tProfile HMMs for sequence families --$g6.$tMultiple sequence alignment methods --$g7.$tBuilding phylogenetic trees --$g8.$tProbabilistic approaches to phylogeny --$g9.$tTransformational grammars --$g10.$tRNA structure analysis --$g11.$tBackground on probability.
520 $aThis book provides the first unified, up-to-date, and tutorial-level overview of sequence analysis methods, with particular emphasis on probabilistic modelling. Pairwise alignment, hidden Markov models, multiple alignment, profile searches, RNA secondary structure analysis, and phylogenetic inference are treated at length.
520 8 $aWritten by an interdisciplinary team of authors, the book is accessible to molecular biologists, computer scientists and mathematicians with no formal knowledge of each others' fields. It presents the state-of-the-art in this important, new and rapidly developing discipline.
650 0 $aNucleotide sequence$xStatistical methods.
650 0 $aAmino acid sequence$xStatistical methods.
650 0 $aNumerical analysis.$0http://id.loc.gov/authorities/subjects/sh85093237
650 0 $aProbabilities.$0http://id.loc.gov/authorities/subjects/sh85107090
650 2 $aBase Sequence.$0https://id.nlm.nih.gov/mesh/D001483
650 2 $aAmino Acid Sequence.$0https://id.nlm.nih.gov/mesh/D000595
650 2 $aNumerical Analysis, Computer-Assisted.$0https://id.nlm.nih.gov/mesh/D009716
650 2 $aProbability.$0https://id.nlm.nih.gov/mesh/D011336
700 1 $aDurbin, Richard.$0http://id.loc.gov/authorities/names/n88185381
852 00 $boff,hsl$hQP620$i.B576 1998
852 00 $bhsl,stx$hQP620$i.B576 1998