Record ID | marc_columbia/Columbia-extract-20221130-009.mrc:82911106:2327 |
Source | marc_columbia |
Download Link | /show-records/marc_columbia/Columbia-extract-20221130-009.mrc:82911106:2327?format=raw |
LEADER: 02327mam a2200361 a 4500
001 4064881
005 20221027030352.0
008 001025t20002000mauaf b 001 0 eng d
020 $a0738201952 :$c$26.00
035 $a(OCoLC)ocm45226067
035 $9ATF2024HS
035 $a(NNC)4064881
035 $a4064881
040 $aZZC$cZZC$dUV$$dNNC-M$dOrLoB-B
090 $aRC523.2$b.D43 2000
092 $a616.831042$bTANZI 2000
100 1 $aTanzi, Rudolph E.$0http://id.loc.gov/authorities/names/n96802784
245 10 $aDecoding darkness :$bthe search for the genetic causes of Alzheimer's disease /$cRudolph E. Tanzi, Ann B. Parson.
260 $aCambridge, Mass. :$bPerseus Publishing,$c[2000], ©2000.
300 $axviii, 281 pages, 8 unnumbered pages of plates :$billustrations, portraits ;$c24 cm
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
504 $aIncludes bibliographical references and index.
505 00 $g1.$tCleave, Zap, Blot, Probe --$g2.$tThe Core of the Matter --$g3.$tCandidate Chromosome --$g4.$tGone Fishing --$g5.$tCurious Gene --$g6.$tFrom Famine to Feast --$g7.$tMutations, Revelations --$g8.$tOf Mice and People --$g9.$tGene Prix --$g10.$tThe 42 Nidus --$g11.$tUntangling a Cascade --$g12.$tA Gamble for Hope.
520 1 $a"Working from the intriguing hypothesis that Alzheimer's dementia is the result of a renegade protein - beta amyloid - Tanzi and others set out to find the gene responsible for its production. Tanzi and science writer Ann Parson take us deep into the minds and far-flung labs of many a prominent researcher.
520 8 $aIn the process, they offer an intimate view of the high stakes of molecular genetics, the revolution that propels it, the obstacles that threaten to derail it, and the families whose lives are so dependent upon it."--BOOK JACKET.
650 0 $aAlzheimer's disease.$0http://id.loc.gov/authorities/subjects/sh85004080
650 0 $aAlzheimer's disease$xGenetic aspects.
650 0 $aAmyloid beta-protein.$0http://id.loc.gov/authorities/subjects/sh92004712
650 2 $aAlzheimer Disease.$0https://id.nlm.nih.gov/mesh/D000544
650 2 $aAmyloid beta-Peptides.$0https://id.nlm.nih.gov/mesh/D016229
700 1 $aParson, Ann B.$0http://id.loc.gov/authorities/names/n95033026
852 00 $boff,hsl$hRC523.2$i.D43 2000