MARC Record from marc_columbia

LEADER: 04037cam a22004094a 4500
001 4827741
005 20221103043822.0
008 020509t20032003maua b 001 0 eng
010 $a 2002071233
015 $aGBA3-65696
016 7 $a101165700$2DNLM
020 $a1405103361 (pbk.)
035 $a(OCoLC)ocm49795681
035 $a(NNC)4827741
035 $a4827741
040 $aDLC$cDLC$dC#P$dCOU$dNLM$dUKM$dOrLoB-B
042 $apcc
050 00 $aQH440$b.H39 2003
060 00 $a2003 B-118
060 10 $aQH 441$bH396a 2003
082 00 $a576.5/072$221
100 1 $aHawley, R. Scott.$0http://id.loc.gov/authorities/names/nb97074266
245 10 $aAdvanced genetic analysis :$bfinding meaning in a genome /$cR. Scott Hawley and Michelle Y. Walker.
260 $aMalden, Mass. :$bBlackwell Pub.,$c[2003], ©2003.
300 $axv, 239 pages :$billustrations ;$c25 cm
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
504 $aIncludes bibliographical references (p. [220]-235) and indexes.
505 00 $gCh. 1.$tMutation -- $g1.1.$tTypes of mutations -- $g1.2.$tDominance and recessivity -- $g1.3.$tThe genetic utility of dominant and recessive mutants -- $gCh. 2.$tMutant hunts -- $g2.1.$tWhy look for new mutants? -- $g2.2.$tMutagenesis and mutational mechanisms -- $g2.3.$tWhat phenotype should you screen (or select) for? -- $g2.4.$tActually getting started -- $gCh. 3.$tThe complementation test -- $g3.1.$tThe essence of the complementation test -- $g3.2.$tRules for using the complementation test -- $g3.3.$tHow might the complementation test lie to you? -- $g3.4.$tSecond-site non-complementation (SSNC) (non-allelic non-complementation) -- $g3.5.$tAn extension of second-site non-complementation: dominant enhancers -- $gCh. 4.$tSuppression -- $g4.1.$tA basic definition of genetic suppression -- $g4.2.$tIntragenic suppression (pseudo-reversion) -- $g4.3.$tExtragenic suppression -- $g4.4.$tTranscriptional suppression -- $g4.5.$tTranslational suppression -- $g4.6.$tSuppression by post-translational modification -- $g4.7.$tExtragenic suppression as a result of protein-protein interaction -- $g4.8.$tSuppression without physical interaction -- $g4.9.$tSuppression of dominant mutations -- $g4.10.$tDesigning your own screen for suppressor mutations -- $gCh. 5.$tDetermining when and where genes function -- $g5.1.$tEpistasis: ordering gene function in pathways -- $g5.2.$tMosaic analysis: where does a given gene act? -- $gCh. 6.$tGenetic fine-structure analysis -- $g6.1.$tIntragenic mapping (then) -- $g6.2.$tIntragenic mapping (now) -- $g6.3.$tIntragenic complementation meets intragenic recombination: the basis of fine-structure analysis -- $g6.4.$tAn example of fine-structure analysis for a eukaryotic gene encoding a multifunctional protein -- $g6.5.$tFine-structure analysis of genes with complex regulatory elements in eukaryotes -- $g6.6.$tPairing-dependent intragenic complementation -- $gCh. 7.$tMeiotic recombination -- $g7.1.$tAn introduction to meiosis -- $g7.2.$tCrossingover and chiasmata: recombination involves the physical interchange of genetic material and ensures homolog separation -- $g7.3.$tThe classical analysis of recombination -- $g7.4.$tMeasuring the frequency of recombination -- $g7.5.$tThe mechanism of recombination -- $gCh. 8.$tMeiotic chromosome segregation -- $g8.1.$tTypes and consequences of failed segregation -- $g8.2.$tThe origin of spontaneous nondisjunction -- $g8.3.$tThe centromere -- $g8.4.$tSegregational mechanisms.
650 0 $aGenetics$xResearch$xMethodology.
650 12 $aGenetic Techniques.$0https://id.nlm.nih.gov/mesh/D005821
650 22 $aGenome.$0https://id.nlm.nih.gov/mesh/D016678
650 22 $aMeiosis.$0https://id.nlm.nih.gov/mesh/D008540
650 22 $aMutagenesis$xgenetics.$0https://id.nlm.nih.gov/mesh/D016296Q000235
650 22 $aRecombination, Genetic.$0https://id.nlm.nih.gov/mesh/D011995
700 1 $aWalker, Michelle Y.$0http://id.loc.gov/authorities/names/n2002017811
852 00 $boff,bio$hQH440$i.H39 2003