| Record ID | marc_columbia/Columbia-extract-20221130-012.mrc:86070302:3221 |
| Source | marc_columbia |
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LEADER: 03221pam a22004574a 4500
001 5593161
005 20221121190833.0
008 040715t20052005fluaf b 001 0 eng
010 $a 2004055375
016 7 $a101224949$2DNLM
020 $a0415334020 (alk. paper)
029 1 $aNLM$b101224949
035 $a(OCoLC)ocm56057999
035 $a(NNC)5593161
035 $a5593161
040 $aDNLM/DLC$cDLC$dYDX$dNLM$dMUQ$dBAKER$dOrLoB-B
042 $apcc
050 00 $aQP601.5$b.E5945 2005
060 00 $a2005 F-582
060 10 $aQU 143$bE6154 2005
082 00 $a615/.35$222
245 00 $aEnzymes and their inhibition :$bdrug development /$cedited by H. John Smith and Claire Simons.
260 $aBoca Raton :$bCRC Press,$c[2005], ©2005.
300 $a308 pages, 4 unnumbered pages of color plates :$billustrations ;$c25 cm.
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
490 1 $aCRC enzyme inhibitors series
504 $aIncludes bibliographical references and index.
505 00 $gCh. 1.$tEnzyme structure and function /$rEdward A. Meighen -- $gCh. 2.$tMechanisms /$rBruce A. Palfey -- $tCytochrome P450 example /$rW. Edward Lindup and Neil R. Kitteringham -- $tCarbonic anhydrase example /$rClaudiu T. Supuran, Andrea Scozzafava and Angela Casini -- $tProteases example /$rAndre J. Niestroj and Hans-Ulrich Demuth -- $gCh. 3.$tKinetics /$rIrene Lee and Anthony J. Berdis -- $gCh. 4.$tEnzyme inhibitors /$rJure Stojan -- $gCh. 5.$tDevelopment of enzyme inhibitors as drugs /$rH. John Smith and Claire Simons -- $tEnzyme inhibitor examples for the treatment of breast cancer /$rL. W. Lawrence Woo -- $tEnzyme inhibitor examples for the treatment of prostate tumor /$rSamer Haidar and Rolf W. Hartmann -- $tThrombin inhibitor examples /$rTorsten Steinmetzer -- $tHIV-1 protease drug development examples /$rPaul J. Ala and Chong-Hwan Chang -- $tMetalloproteinase-collagenase inhibitor examples /$rClaudiu T. Supuran and Andrea Scozzafava.
520 1 $a"Focusing on the development of enzyme inhibitors as therapeutic drugs, Enzymes and Their Inhibition: Drug Development provides a concise overview of the chemistry of major types of enzymes and their inhibitors. The opening chapters introduce the structure, substrates, kinetics, and mechanisms of enzymes. Subsequent chapters discuss the different types of enzyme inhibitors and the principles involved in developing them into effective drugs."--BOOK JACKET.
650 0 $aEnzyme inhibitors.$0http://id.loc.gov/authorities/subjects/sh85044226
650 0 $aDrug development.$0http://id.loc.gov/authorities/subjects/sh97007921
650 12 $aEnzyme Inhibitors.$0https://id.nlm.nih.gov/mesh/D004791
650 22 $aChemistry, Pharmaceutical.$0https://id.nlm.nih.gov/mesh/D002626
650 22 $aDrug Design.$0https://id.nlm.nih.gov/mesh/D015195
650 6 $aAntienzymes.
650 6 $aMédicaments$xDéveloppement.
700 1 $aSmith, H. J.,$d1930-$0http://id.loc.gov/authorities/names/n87842802
700 1 $aSimons, Claire.$0http://id.loc.gov/authorities/names/no2001040332
830 0 $aCRC enzyme inhibitors series.$0http://id.loc.gov/authorities/names/n2003005534
852 00 $boff,hsl$hQP601.5$i.E5945 2005