MARC Record from marc_columbia

LEADER: 03564cam a22004338a 4500
001 6934488
005 20221130192845.0
008 080409t20082008nyu 101 0 eng
010 $a 2008925169
015 $aGBA856507$2bnb
016 7 $a014589354$2Uk
020 $a9780387789514 (hbk.)
020 $a0387789510 (hbk.)
029 1 $aOHX$bhar080060849
035 $a(OCoLC)ocn225427610
035 $a(OCoLC)225427610
035 $a(NNC)6934488
035 $a6934488
040 $aUKM$cUKM$dBTCTA$dBAKER$dYDXCP$dOHX$dOCLCG$dCUS$dBWX$dPAU$dCOU$dOrLoB-B
050 4 $aR850.A1$bA39 v.632 2008
082 04 $a616.079$222
096 $aW1 AD584 v.632
111 2 $aWorkshop on Complement Associated Diseases, Animal Models, and Therapeutics$n(4th :$d2007 :$cPortokhélion, Greece)
245 10 $aCurrent topics in complement.$nII /$cJohn D. Lambris, editor.
246 3 $aCurrent topics in complement.$n2
260 $aNew York ;$aLondon :$bSpringer,$c[2008], ©2008.
300 $axxx, 316 pages :$billustrations ;$c25 cm.
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
490 1 $aAdvances in experimental medicine and biology ;$vv. 632
500 $aSelected conference papers.
504 $aIncludes bibliographical references and index.
520 1 $a"Complement has long been regarded as a pivotal effector arm of the innate immune response, eliciting important immunoregulatory functions in the context of inflammation and also serving as a vital link between the innate and adaptive immune response. In the post-genomic era, our knowledge of the innate immune system is enriched by findings that point to novel functions that do not strictly correlate with immunological defense and surveillance, immune modulation or inflammation. Several studies indicate that complement proteins exert functions that are either more complex than previously thought, or go well beyond the innate immune character of the system. The advent of high-throughput platforms for genome and proteome-wide profiling, together with the enormous amount of raw genetic information that has accumulated in the databases, have stirred new expectations in biomedical research. They have led complementologists to revisit established biological systems, such as the complement system, from a global and integrative perspective. Complement research is now faced with the challenge of trying to integrate isolated biochemical pathways into complex gene and protein regulatory circuits." "In this respect, scientists from around the world convened at the Fourth Aegean Conferences Workshop on Complement Associated Diseases, Animal Models, and Therapeutics (June 10-15, 2007), to discuss recent advances in this fast evolving field. This volume represents a collection of topics on the "novel" functions of complement, patho-physiology, protein structures, design of complement inhibitors, and complement assays discussed during the conference." "The book is written for immunologists, microbiologists, pathologists, and specialists in infectious disease and inflammation."--BOOK JACKET.
650 0 $aComplement (Immunology)$vCongresses.
650 2 $aComplement System Proteins$ximmunology.$0https://id.nlm.nih.gov/mesh/D003165Q000276
655 2 $aCongress.$0https://id.nlm.nih.gov/mesh/D016423
700 1 $aLambris, J. D.$q(John D.)$0http://id.loc.gov/authorities/names/n89124132
830 0 $aAdvances in experimental medicine and biology ;$vv. 632.$0http://id.loc.gov/authorities/names/n42001229
852 00 $boff,hsl$hQR185.8.C6$iC97 2008