| Record ID | marc_columbia/Columbia-extract-20221130-014.mrc:142070002:3712 |
| Source | marc_columbia |
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LEADER: 03712cam a22004334a 4500
001 6936907
005 20221130193221.0
008 080703t20092009njuaf b 001 0 eng
010 $a 2008029786
016 7 $a101478607$2DNLM
020 $a9780470086797 (cloth)
020 $a0470086793 (cloth)
029 1 $aNLM$b101478607
035 $a(OCoLC)ocn230180300
035 $a(OCoLC)230180300
035 $a(NNC)6936907
035 $a6936907
040 $aDNLM/DLC$cDLC$dNLM$dBTCTA$dBAKER$dYDXCP$dC#P$dOrLoB-B
042 $apcc
050 00 $aRM301.55$b.N83 2009
060 10 $aQV 38$bN964 2009
082 00 $a615/.7$222
245 00 $aNuclear receptors in drug metabolism /$cedited by Wen Xie.
260 $aHoboken, NJ :$bJohn Wiley & Sons,$c[2009], ©2009.
300 $axxii, 330 pages, 8 unnumbered pages of plates :$billustrations (some color) ;$c25 cm
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
504 $aIncludes bibliographical references and index.
505 00 $g1.$tDrug Metabolism: Significance and Challenges /$rChandra Prakash and Alfin D. N. Vaz -- $g2.$tEstablishing Orphan Nuclear Receptors PXR and CAR as Xenobiotic Receptors /$rTao Li, Junichiro Sonoda and Ronald M. Evans -- $g3.$tNuclear Receptor-Mediated Regulation of Phase II Conjugating Enzymes /$rOlivier Barbier -- $g4.$tNuclear Receptor-Mediated Regulation of Drug Transporters /$rOliver Burk -- $g5.$tStructure and Function of PXR and CAR /$rX. Edward Zhou and H. Eric Xu -- $g6.$tXenobiotic Receptor Cofactors and Coregulators /$rJohn Y. L. Chiang -- $g7.$tAnimal Models of Xenobiotic Nuclear Receptors and Their Utility in Drug Development /$rHaibiao Gong and Wen Xie -- $g8.$tNuclear Receptors and Drug-Drug Interactions with Prescription and Herbal Medicines /$rRommel G. Tirona and Richard B. Kim -- $g9.$tGenetic Variants of Xenobiotic Receptors and Their Implications in Drug Metabolism and Pharmacogenetics /$rJatinder Lamba and Erin G. Schuetz -- $g10.$tBeyond PXR and CAR, Regulation of Xenobiotic Metabolism by Other Nuclear Receptors /$rMartin Wagner, Gernot Zollner and Michael Trauner -- $g11.$tEmerging Role of Retinoid-Related Orphan Receptor (ROR) and Its Cross Talk with LXR (Liver X Receptor) in the Regulation of Drug-Metabolizing Enzymes /$rTaira Wada and Wen Xie.
520 1 $a"Integrating the findings from several disciplines, Nuclear Receptors in Drug Metabolism enables readers to more accurately predict drug metabolism and drug-drug interactions as well as physiological outcomes. It offers a comprehensive review of the role of nuclear hormone receptors as transcriptional regulators of drug-metabolizing enzymes and transporters, helping readers understand what's known, what's in development, and what's on the horizon. In addition to drug metabolism and drug development, the book also emphasizes clinical drug use, therapeutic potentials, and pharmacogenetics."--BOOK JACKET.
650 0 $aDrugs$xMetabolism.$0http://id.loc.gov/authorities/subjects/sh85039737
650 0 $aNuclear receptors (Biochemistry)$0http://id.loc.gov/authorities/subjects/sh96008334
650 0 $aGenetic regulation.$0http://id.loc.gov/authorities/subjects/sh85053870
650 12 $aReceptors, Cytoplasmic and Nuclear$xmetabolism.$0https://id.nlm.nih.gov/mesh/D018160Q000378
650 22 $aDrug Delivery Systems$xmethods.$0https://id.nlm.nih.gov/mesh/D016503Q000379
650 22 $aPharmaceutical Preparations$xmetabolism.$0https://id.nlm.nih.gov/mesh/D004364Q000378
650 22 $aReceptors, Steroid$xmetabolism.$0https://id.nlm.nih.gov/mesh/D011987Q000378
700 1 $aXie, Wen,$d1967-$0http://id.loc.gov/authorities/names/n2008046352
852 00 $boff,hsl$hRM301.55$i.N83 2009