MARC Record from marc_columbia

LEADER: 03543cam a22003738a 4500
001 7140869
005 20221130211048.0
008 080702s2009 njua b 001 0 eng
020 $a9781603273060 (hbk.)
020 $a1603273069 (hbk.)
024 $a40016541121
035 $a(OCoLC)233933790
035 $a(OCoLC)ocn233933790
035 $a(NNC)7140869
035 $a7140869
040 $aUKM$cUKM$dBTCTA$dBAKER$dYDXCP$dNNC$dOrLoB-B
082 04 $a616.99407$222
245 00 $aTelomeres and telomerase in cancer /$cKeiko Hiyama, editor.
260 $aTotowa, N.J. :$bHumana ;$aLondon :$bSpringer [distributor],$c2009.
300 $axii, 373 pages :$billustrations (some color) ;$c24 cm.
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
490 1 $aCancer drug discovery and development
504 $aIncludes bibliographical references and index.
505 00 $gPt. I.$tBasic Background -- $g1.$tTelomeres and Telomerase in Humans /$rKeiko Hiyama, Eiso Hiyama and Jerry W. Shay -- $g2.$tTelomere-Binding Proteins in Humans /$rNadya Dimitrova -- $g3.$tRegulation of Telomerase Through Transcriptional and Posttranslational Mechanisms /$rAmy N. Depcrynski, Patrick C. Sachs, Lynne W. Elmore and Shawn E. Holt -- $g4.$tTelomere Dysfunction and the DNA Damage Response /$rMalissa C. Diehl, Lynne W. Elmore and Shawn E. Holt -- $g5.$tAlternative Lengthening of Telomeres in Human Cells /$rHilda A. Pickett and Roger R. Reddel -- $g6.$tMouse Model: Telomeres and Telomerase in Stem Cell and Cancer /$rXin Huang and Zhenyu Ju -- $gPt. II.$tTelomeres and Telomerase in Human Cancers -- $g7.$tRole of Telomeres and Telomerase in Cancer /$rKeiko Hiyama, Eiso Hiyama, Keiji Tanimoto and Masahiko Nishiyama -- $g8.$tDiagnostic Value I: Solid Tumors /$rEiso Hiyama and Keiko Hiyama -- $g9.$tDiagnostic Value II: Hematopoietic Malignancies /$rJunko H. Ohyashiki and Kazuma Ohyashiki -- $g10.$tTherapeutic Targets and Drugs I: Telomerase and Telomerase Inhibitors /$rBrittney-Shea Herbert and Erin M. Goldblatt -- $g11.$tTherapeutic Targets and Drugs II: G-Quadruplex and G-Quadruplex Inhibitors /$rChandanamali Punchihewa and Danzhou Yang -- $g12.$tTherapeutic Targets and Drugs III: Tankyrase 1, Telomere-Binding Proteins, and Inhibitors /$rHiroyuki Seimiya and Takashi Tsuruo -- $g13.$tTherapeutic Targets and Drugs IV: Telomerase-Specific Gene and Vector-Based Therapies for Human Cancer /$rToshiyoshi Fujiwara, Yasuo Urata and Noriaki Tanaka -- $gPt. III.$tExperimental Protocols -- $g14.$tProtocol I: Telomerase Activity and Telomerase Expression /$rEiso Hiyama -- $g15.$tProtocol II: Importance and Methods of Telomere G-Tail Length Quantification /$rAkira Shimamoto, Eriko Aoki, Angie M. Sera and Hidetoshi Tahara -- $g16.$tProtocol III: Detection of Alternative Lengthening of Telomeres /$rWei-Qin Jiang, Jeremy D. Henson, Axel A. Neumann and Roger R. Reddel.
650 0 $aCancer$xMolecular aspects.$0http://id.loc.gov/authorities/subjects/sh89006610
650 0 $aTelomerase.$0http://id.loc.gov/authorities/subjects/sh97007324
650 0 $aTelomere.$0http://id.loc.gov/authorities/subjects/sh94005630
650 12 $aNeoplasms.$0https://id.nlm.nih.gov/mesh/D009369
650 22 $aTelomerase.$0https://id.nlm.nih.gov/mesh/D019098
650 22 $aTelomere.$0https://id.nlm.nih.gov/mesh/D016615
700 1 $aHiyama, Keiko.$0http://id.loc.gov/authorities/names/no2009064094
830 0 $aCancer drug discovery and development.$0http://id.loc.gov/authorities/names/n88538383
852 00 $boff,sci$hRC268.4$i.T45 2008g