| Record ID | marc_columbia/Columbia-extract-20221130-016.mrc:177398990:3460 |
| Source | marc_columbia |
| Download Link | /show-records/marc_columbia/Columbia-extract-20221130-016.mrc:177398990:3460?format=raw |
LEADER: 03460cam a22003855a 4500
001 7976832
005 20221201050724.0
008 100427s2010 njua b 001 0 eng
015 $aGBB060991$2bnb
016 7 $a015551384$2Uk
020 $a9781607617587 (hbk.)
020 $a1607617587 (hbk.)
035 $a(OCoLC)ocn615896345
035 $a(NNC)7976832
035 $a(OCoLC)615896345
035 $a7976832
040 $aUKM$cUKM$dYDXCP
082 04 $a616.994042$222
245 00 $aCancer susceptibility :$bmethods and protocols /$cedited by Michelle Webb.
260 $aTotowa, N.J. :$bHumana ;$aLondon :$bSpringer [distributor],$c2010.
300 $axi, 295 pages :$billustrations (some color) ;$c27 cm.
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
490 1 $aSpringer protocols
490 1 $aMethods in molecular biology ;$v653
504 $aIncludes bibliographical references and index.
505 0 $ahe identification of colon cancer susceptibility genes by using genome-wide scans -- Prioritizing candidate genetic modifiers of BRCA1 and BRCA2 using a combinatorial analysis of global expression and polymorphism association studies of breast cancer -- Microarray-based comparative genomic hybridization (array-CGH) as a useful tool for identifying genes involved in Glioblastoma (GB) -- Multiplex Amplifiable Probe Hybridization (MAPH) methodology as an alternative to comparative genomic hybridization (CGH) -- Utilizing Saccharomyces cerevisiae to identify aneuploidy and cancer susceptibility genes -- Computational identification of cancer susceptibility loci -- Digital candidate gene approach (DigiCGA) for identification of cancer genes -- The use of denaturing high performance liquid chromatography (DHPLC) for mutation scanning of hereditary cancer genes -- Enhanced mismatch mutation analysis: simultaneous detection of point mutations and large scale rearrangements by capillary electrophoresis, application to BRCA1 and BRCA2 -- Economical protocol for combined single-strand conformation polymorphism and heteroduplex analysis on a standard capillary electrophoresis apparatus -- Mutational screening of hMLH1 and hMSH2 that confer inherited colorectal cancer susceptibility using denature gradient gel electrophoresis (DGGE) -- s-RT-MELT: a novel technology for mutation screening -- Zoom-in array comparative genomic hybridization (aCGH) to detect germline rearrangements in cancer susceptibility genes -- Development of a scoring system to screen for BRCA1/2 mutations -- Use of splicing reporter minigene assay to evaluate the effect on splicing of unclassified genetic variants -- Functional analysis of human BRCA2 variants using a mouse embryonic stem cell-based assay -- Developing functional assays for BRCA1 unclassified variants.
650 0 $aCancer$xSusceptibility.$0http://id.loc.gov/authorities/subjects/sh89006016
650 0 $aCancer$xGenetic aspects.$0http://id.loc.gov/authorities/subjects/sh85019509
650 12 $aNeoplasms.$0https://id.nlm.nih.gov/mesh/D009369
650 22 $aGenetic Predisposition to Disease.$0https://id.nlm.nih.gov/mesh/D020022
700 1 $aWebb, Michelle.$0http://id.loc.gov/authorities/names/n96069320
830 0 $aSpringer protocols (Series)$0http://id.loc.gov/authorities/names/no2008180772
830 0 $aMethods in molecular biology (Clifton, N.J.) ;$vv. 653.$0http://id.loc.gov/authorities/names/n92002874
852 00 $boff,hsl$hQH506$i.M56 v.653