MARC Record from marc_columbia

LEADER: 05369cam a2200445 a 4500
001 10727449
005 20160123210415.0
008 131220t2014 dcua b 000 0 eng d
020 $z9780309288866
020 $z030928886X
035 $a(OCoLC)876881218
035 $a(OCoLC)ocn876881218
035 $a(NNC)10727449
040 $aNNC$dNNC
043 $an-us---$aa-vt---
050 4 $aRA1270.T44$bI578 2012
110 2 $aInstitute of Medicine (U.S.).$bCommittee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides,$eissuing body.
245 10 $aVeterans and agent orange :$bupdate 2012 /$cCommitee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Ninth Biennial Update), Board on the Health of Select Populations, Institute of Medicine of the National Academies.
260 $aWashington, D.C. :$bNational Academies Press,$c2014.
300 $axix, 986 p. :$bill. ;$c24 cm.
504 $aIncludes bibliographical references.
505 0 $aSummary -- 1. Introduction -- 2. Evaluating the evidence -- 3. Exposure to the herbicides used in Vietnam -- 4. Information related to biologic plausibility -- 5. Epidemiologic studies: compendium of new publications -- 6. Epidemiologic studies: background on multiply referenced populations -- 7. Immune-system disorders -- 8. Cancer -- 9. Fertility and gestational outcomes -- 10. Effects on future generations -- 11. Neurologic disorders -- 12. Cardiovascular and metabolic outcomes -- 13. Other chronic health outcomes -- 14. Conclusions and recommendations -- Appendix A: Issues raised by the public and agendas of public meetings held by the Commitee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Ninth Biennial Update) and other written submissions to the Committee -- Appendix B: Short-term adverse health responses -- Appendix C: Clarification of cancer groupings used in reporting results, with correspondence to National Institute for Occupational Safety and Health and health cause-of-death codes and international classification of diseases codes for cancers -- Appendix D: Biographies of Commitee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Ninth Biennial Update) and staff.
520 $a"From 1962 to 1971, the US military sprayed herbicides over Vietnam to strip the thick jungle canopy that could conceal opposition forces, to destroy crops that those forces might depend on, and to clear tall grasses and bushes from the perimeters of US base camps and outlying fire-support bases. Mixtures of 2,4-dichlorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), picloram, and cacodylic acid made up the bulk of the herbicides sprayed. The main chemical mixture sprayed was Agent Orange, a 50:50 mixture of 2,4-D and 2,4,5-T. At the time of the spraying, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the most toxic form of dioxin, was an unintended contaminant generated during the production of 2,4,5-T and so was present in Agent Orange and some other formulations sprayed in Vietnam. Because of complaints from returning Vietnam veterans about their own health and that of their children combined with emerging toxicologic evidence of adverse effects of phenoxy herbicides and TCDD, the National Academy of Sciences (NAS) was asked to perform a comprehensive evaluation of scientific and medical information regarding the health effects of exposure to Agent Orange, other herbicides used in Vietnam, and the various components of those herbicides, including TCDD. Updated evaluations are conducted every two years to review newly available literature and draw conclusions from the overall evidence.Veterans and Agent Orange: Update 2012 reviews peer-reviewed scientific reports concerning associations between health outcomes and exposure to TCDD and other chemicals in the herbicides used in Vietnam that were published in October 2010--September 2012 and integrates this information with the previously established evidence database. This report considers whether a statistical association with herbicide exposure exists, taking into account the strength of the scientific evidence and the appropriateness of the statistical and epidemiological methods used to detect the association; the increased risk of disease among those exposed to herbicides during service in the Republic of Vietnam during the Vietnam era; and whether there exists a plausible biological mechanism or other evidence of a causal relationship between herbicide exposure and the disease"--Publisher's description.
650 0 $aAgent Orange$xToxicology.
650 0 $aVietnam War, 1961-1975$xVeterans$xHealth aspects.
650 0 $aVietnam War, 1961-1975$xVeterans$xDiseases.
650 0 $aHerbicides$xToxicology.
650 0 $aEpidemiology.
650 12 $aHerbicides$xadverse effects.
651 2 $aVietnam.
650 22 $aDioxins$xadverse effects.
650 22 $aEnvironmental Exposure.
650 22 $aVeterans Health.
651 2 $aUnited States.
650 22 $aVietnam Conflict.
651 7 $aUnited States.$2fast$0(OCoLC)fst01204155
648 7 $a1961 - 1975$2fast
856 40 $3National Academies Press$uhttp://www.nap.edu/catalog.php?record_id=18395
856 41 $3National Academies Press$uhttp://www.nap.edu/catalog.php?record_id=18395
852 00 $boff,sci$hRA1270.T44$iI578 2012g