MARC Record from marc_columbia

LEADER: 05124cam a2200493 i 4500
001 11895570
005 20160623140021.0
008 150421s2015 nyua b 001 0 eng
010 $a 2015012098
020 $a9781621821236$q(hardback)
020 $a1621821234$q(hardback)
024 $a99967303719
035 $a(OCoLC)ocn907948373
035 $a(OCoLC)907948373
035 $a(NNC)11895570
040 $aDLC$beng$erda$cDLC$dYDX$dNTE$dYDXCP$dCDX$dSTF$dOCLCF$dNLM$dOCLCQ
042 $apcc
050 00 $aQP625.N89$bN485 2015
060 00 $a2015 I-147
060 10 $aQU 58.5
082 00 $a572.8/633$223
084 $aSCI049000$aSCI029000$aMED107000$2bisacsh
245 00 $aNext-generation DNA sequencing informatics /$cedited by Stuart M. Brown.
250 $aSecond edition.
264 1 $aCold Spring Harbor, New York :$bCold Spring Harbor Laboratory Press,$c[2015]
300 $axiv, 402 pages :$billustrations (some color) ;$c27 cm
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
338 $avolume$bnc$2rdacarrier
520 $a"Next-generation DNA sequencing (NGS) technology has revolutionized biomedical research, making genome and RNA sequencing an affordable and frequently used tool for a wide variety of research applications including variant (mutation) discovery, gene expression, transcription factor analysis, metagenomics, and epigenetics. Bioinformatics methods to support DNA sequencing have become and remain a critical bottleneck for many researchers and organizations wishing to make use of NGS technology. Next-Generation DNA Sequencing Bioinformatics, Second Edition, provides thorough, plain language introduction to the necessary informatics methods and tools for analyzing NGS data as did the first edition, and provides detailed descriptions of algorithms, strengths and weaknesses of specific tools, pitfalls and alternative methods. Four new chapters in this edition cover: experimental design, sample preparation, and quality assessment of NGS data; Public databases for DNA Sequencing data; De novo transcript assembly; proteogenomics; and emerging sequencing technologies. The remaining chapters from the first edition have been updated with the latest information. This book also provides extensive reference to best-practice bioinformatics methods for NGS applications and tutorials for common workflows. The second edition of Next-Generation DNA Sequencing Bioinformatics addresses the informatics needs of students, laboratory scientists, and computing specialists who wish to take advantage of the explosion of research opportunities offered by new DNA sequencing technologies"--$cProvided by publisher.
520 $a"Next-generation DNA sequencing (NGS) technology has revolutionized biomedical research, making complete genome sequencing an affordable and frequently used tool for a wide variety of research applications. This book provides a thorough introduction to the necessary informatics methods and tools for operating NGS instruments and analyzing NGS data"--$cProvided by publisher.
504 $aIncludes bibliographical references and index.
505 0 $a1. Introduction to DNA Sequencing / Stuart M. Brown -- 2. Quality Control and Data Preprocessing / Stuart M. Brown -- 3. History of Sequencing Informatics / Stuart M. Brown -- 4. Public Sequence Databases -- Stuart M. Brown -- 5. Visualization of Next-Generation Sequencing Data / Philip Ross Smith, Kranti Konganti, and Stuart M. Brown -- 6. DNA Sequence Alignment / Efstratios Efstathiadis -- 7. Genome Assembly Using Generalized de Bruijin Digraphs / D. Frank Hsu -- 8. De novo Assembly of Bacterial Genomes from Short Sequence Reads / Silvia Argimón and Stuart M. Brown / 9. De novo Transcriptome Assembly / Lisa Cohen, Steven Shen, and Efstratios Efstathiadis -- 10. Genome Annotation / Steven Shen and Stuart M. Brown -- 11. Using Next-Generation Sequencing to Detect Sequence Variants / Jinhua Wang, Zuojian Tang, and Stuart M. Brown -- 12. ChIP-seq -- Stuart M. Brown, Zuojian Tang, Christina Schweikert, and D. Frank Hsu -- 13. RNA Sequencing with Next-Generation Sequencing / Stuart M. Brown and Jeremy Goecks -- 14. Metagenomics / Guillermo I. Perez-Perez, Miroslav Blumenberg, and Alexander V. Alekseyenko -- 15. Proteogenomics / Kelly V. Ruggles and David Fenyö -- 16. Emerging DNA Sequencing Technologies and Applications / Gerald A. Higgins and Brian D. Athey -- 17. Cloud-based Next-Generation Sequencing Informatics / Konstantinos Krampis, Efstratios Efstathiadis, and Stuart M. Brown -- Glossary -- Index.
650 0 $aNucleotide sequence.
650 0 $aBioinformatics.
650 7 $aSCIENCE$xLife Sciences$xBiology$xMolecular Biology.$2bisacsh
650 7 $aSCIENCE$xLife Sciences$xGenetics & Genomics.$2bisacsh
650 7 $aMEDICAL$xGenetics.$2bisacsh
650 7 $aBioinformatics.$2fast$0(OCoLC)fst00832181
650 7 $aNucleotide sequence.$2fast$0(OCoLC)fst01041106
650 12 $aSequence Analysis, DNA.
650 22 $aComputational Biology$xmethods.
700 1 $aBrown, Stuart M.,$d1962-
852 00 $boff,sci$hQP625.N89$iN485 2015