MARC Record from marc_columbia

LEADER: 03528cam a2200397Ii 4500
001 13430192
005 20180820124403.0
008 180628t20182018dcua 100 0 eng d
020 $a9780309471169
020 $a0309471168
035 $a(OCoLC)on1042161471
035 $a(OCoLC)1042161471
035 $a(NNC)13430192
040 $aNRC$beng$erda$cNRC$dEEM$dOCLCF
050 04 $aR853 .A53$bF67 2017
100 1 $aForstag, Erin Hammers,$erapporteur.
245 10 $aAdvancing disease modeling in animal-based research in support of precision medicine :$bproceedings of a workshop /$cErin Hammers Forstag and Lida Anestidou, rapporteurs ; Roundtable on Science and Welfare in Laboratory Animal Use, Institute for Laboratory Animal Research, Division of Earth and Life Studies, the National Academies of Sciences, Engineering, Medicine.
264 1 $aWashington, DC :$bthe Nationeal Academies Press,$c[2018]
264 4 $c©2018.
300 $axiii, 122 pages :$bcolor illustrations ;$c23
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
338 $avolume$bnc$2rdacarrier
504 $aIncludes bibliographical references (pages 90-94).
505 0 $aIntroduction to precision medicine and animal models -- Existing precision medicine initiatives -- The promise and perils of animal models -- Reproducibility and predictivity -- In vitro alternatives to animal models -- Assessing safety and toxicology -- Patient perspectives -- Reflections on the workshop -- References.
520 $a"Precision medicine is focused on the individual and will require the rapid and accurate identification and prioritization of causative factors of disease. To move forward and accelerate the delivery of the anticipated benefits of precision medicine, developing predictable, reproducible, and reliable animal models will be essential. In order to explore the topic of animal-based research and its relevance to precision medicine, the National Academies of Sciences, Engineering, and Medicine convened a 2-day workshop on October 5 and 6, 2017. The workshop was designed to focus on the development, implementation, and interpretation of model organisms to advance and accelerate the field of precision medicine. Participants examined the extent to which next-generation animal models, designed using patient data and phenotyping platforms targeted to reveal and inform disease mechanisms, will be essential to the successful implementation of precision medicine. This publication summarizes the presentations and discussions from the workshop"--Publisher's description.
650 0 $aAnimal models in research$vCongresses.
650 0 $aPersonalized medicine$vCongresses.
650 7 $aAnimal models in research.$2fast$0(OCoLC)fst00809302
650 7 $aPersonalized medicine.$2fast$0(OCoLC)fst01910010
655 7 $aConference papers and proceedings.$2fast$0(OCoLC)fst01423772
700 1 $aAnestidou, Lida,$d1965-$erapporteur.
710 2 $aNational Academies of Sciences, Engineering, and Medicine (U.S.).$bRoundtable on Science and Welfare in Laboratory Animal Use,$eissuing body.
711 2 $aAdvancing Disease Modeling in Animal-Based Research in Support of Precision Medicine (Workshop)$d(2017 :$cWashington, D.C.)
776 08 $iOnline version:$aForstag, Erin Hammers.$tAdvancing disease modeling in animal-based research in support of precision medicine : proceedings of a Workshop$dWashington, D.C. : National Academies Press,$c2018$w(OCoLC)1039686906
852 00 $boff,sci$hR853 .A53$iF67 2017g