MARC Record from marc_columbia

LEADER: 05812cam a2200625Ia 4500
001 13074175
005 20180416145156.0
006 m o d
007 cr cn|||||||||
008 110214s2010 si a ob 001 0 eng d
019 $a729020953$a764546173$a816583890$a858443312$a961531319$a962574728$a968290398$a988475514$a990539135$a992035708
020 $a9781615836888$q(electronic bk.)
020 $a1615836888$q(electronic bk.)
020 $a9789814295680$q(e-book)
020 $a981429568X$q(e-book)
020 $a1282763547
020 $a9781282763548
020 $z9789814295673
020 $z9814295671
035 $a(OCoLC)681789053
035 $a(OCoLC)ocn681789053
035 $a(NNC)13074175
037 $bKnovel Corporation$nhttp://www.knovel.com
040 $aKNOVL$beng$epn$cKNOVL$dOCLCQ$dCUY$dCBT$dCOO$dOCLCO$dOCLCQ$dKNOVL$dOCLCA$dZCU$dKNOVL$dOCLCF$dKNOVL$dCNNAI$dOCLCQ$dAZK$dLOA$dOCLCO$dMOR$dLIP$dIDEBK$dPIFAG$dMERER$dOCLCQ$dOCLCO$dOCLCA$dBUF$dOCLCO
050 4 $aR857.M3$bB4767 2010eb
060 00 $a2010 G-444
060 10 $aQT 37
072 7 $aMQW, TGM$2bicssc
082 04 $a610.28$222
245 00 $aBiologically-responsive hybrid biomaterials :$ba reference for material scientists and bioengineers /$ceditors, E. Jabbari, A. Khademhosseini.
260 $aSingapore ;$aHackensack, NJ :$bWorld Scientific,$c©2010.
300 $a1 online resource (vi, 423 pages) :$billustrations (some color)
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
347 $adata file$2rda
504 $aIncludes bibliographical references and index.
505 0 $aEngineering the tissue extracellular matrix with hybrid biomaterials -- Synthesis, characterization and self-assembly -- Bulk and solution properties of peptide-polymer conjugates -- Polymer-peptide conjugate networks: formation, swelling and degradation -- Peptide self-assembly biomaterials design and application -- Micropatterned polymer structures for cell and tissue engineering -- Synthesis and in vitro/in vivo response to peptide-polymer conjugates -- Hybrid biomaterials in drug delivery and molecular recognition -- Synthesis of multi-epitopic glycopeptide-based cancer vaccines -- Stimuli-sensitive particles for drug delivery -- Design and synthesis of endosomolytic conjugated polyaspartamide for cytosolic drug delivery -- Engineering of cell-penetrating peptide-conjugated intracellular delivery systems -- Cell responsive biomaterials in tissue engineering -- Biomimetic matrices for integrin-mediated cell adhesion -- Engineering artificial stem cell niches -- Engineering peptides in hydrogels for cartilage tissue regeneration -- Biomimetic materials for engineering of neural tissues: control of cell adhesion and guiding neural cell outgrowth with peptide-conjugated polymer structures -- Hybrid biomaterials for engineering vascular tissues -- Dynamic cell culture methods for functionalized biomaterials.
588 0 $aPrint version record.
520 $aConjugation of synthetic materials with cell-responsive biologically-active molecules, in addition to providing structural support and release of biomolecules in the regenerating region, can provide the signaling factors required to initiate the cascade of cell migration, adhesion, differentiation, maturation, growth factor modulation, maintenance of matrix integrity, and tissue morphogenesis. Nanoparticles conjugated with ligands that preferentially interact with cell surface receptors in the tumor environment have the potential to drastically improve bioavailability, selectivity and residence time of the chemotherapeutic agent in the tumor microenvironment, while limiting their peripheral toxicity. Multivalent presentation of tumor-associated antigens on a targeted delivery system containing T and B cell epitopes can result in strong, long-lasting, self-adjuvant immunity against cancer and other diseases in vaccination. These examples demonstrate that cell-responsive conjugate biomaterials have profoundly impacted the medical field. This book is divided into three sections. In the first section, synthesis and characterization, conformation, structure-activity, self-assembly, and host response of conjugate hybrid biomaterials are covered. The second section is dedicated to the applications of conjugate biomaterials in drug delivery and vaccination while the last section is devoted to tissue engineering applications including cell adhesion, control of the stem cell niche, cartilage regeneration, neural and vascular tissue engineering, and dynamic cell culture systems for functionalized biomaterials. There is no doubt that biologically-responsive conjugate biomaterials play a key role in the design of biologics and medical devices, and this pioneering reference book provides a comprehensive review on synthesis, characterization, structure-activity, 3D assembly/fabrication, host response and the emerging applications of conjugate hybrid biomaterials.
546 $aEnglish.
650 0 $aBiomedical materials.
650 7 $aBiomedical materials.$2fast$0(OCoLC)fst00832586
650 12 $aBiocompatible Materials.
650 22 $aBiomimetic Materials.
650 22 $aCells, Cultured.
650 22 $aDrug Delivery Systems.
650 22 $aStructure-Activity Relationship.
650 22 $aTissue Engineering.
655 4 $aElectronic books.
700 1 $aJabbari, E.$q(Esmaiel)
700 1 $aKhademhosseini, Ali.
776 08 $iPrint version:$tBiologically-responsive hybrid biomaterials.$dSingapore ; Hackensack, NJ : World Scientific, ©2010$z9789814295673$w(OCoLC)496951838
856 40 $uhttp://www.columbia.edu/cgi-bin/cul/resolve?clio13074175$zACADEMIC - Biochemistry, Biology & Biotechnology
852 8 $blweb$hEBOOKS