MARC Record from marc_columbia

LEADER: 07923cam a22007574i 4500
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005 20190730121623.0
008 090708t20092009gw a b 001 0 eng
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019 $a779896449
020 $a9783527323302$q(paperback)
020 $a3527323309$q(paperback)
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035 $a(OCoLC)277069160$z(OCoLC)779896449
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050 00 $aQD415$b.C456 2009
082 04 $a547$222
084 $aCHE 800f$2stub
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245 00 $aChemical biology :$blearning through case studies /$cedited by Herbert Waldmann and Petra Janning.
264 1 $aWeinheim :$bWiley-VCH Verpag GmbH & Co. KGaA,$c[2009]
264 4 $c©2009
300 $axxxiii, 271 pages :$billustrations (some color) ;$c25 cm
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
338 $avolume$bnc$2rdacarrier
504 $aIncludes bibliographical references and index.
505 0 $aYeast-based chemical genomic approaches / Katja Hubel -- Microarray-based strategies to identify unknown protein / Sabine Borgmann and Christof M. Niemeyer -- Compound collection synthesis for chemical biology / Kamal Kumar -- Target identification and validation of a WNT/P-catenin pathway modulator / Petra Janning -- Activity-based protein profiling of cys proteases / Renier van der Hoorn -- The use of photoaffinity labeling for the identification of the binding site of the antibiotic linezolid / Rolf Breinbauer and Matthias Mentel -- Surgical strikes : uses of analog sensitive technologies to target kinases of interest / Matthias Rabiller and Daniel Rauh -- Modulation of protein-protein interactions by small molecules / Stefanie Bovens and Christian Ottmann -- Targeted protein degradation in live cells / Markus Kaiser -- Trapoxin B : from total synthesis to epigenetics / Bruno Bulic -- Native chemical ligation : a tool for chemical protein synthesis / Christian F.W. Becker -- Using split inteins to prepare semi-synthetic proteins and to study the mechanism of protein trans-splicing / Henning D. Mootz -- Elucidation of the ras cycle with semi-synthetic proteins / Luc Brunsveld -- The study of rab GTpase recycling using semi-synthetic prenylated proteins / Kirill Alexandrov [and others] -- Development of a model cancer vaccine candidate based on the MUC1 cellular surface glycopeptide epitope / Christian Hedberg and Ulrika Westerlind -- The introduction of chemical reporter groups by bioorthogonal ligation reactions for the imaging of cell-surface glycans / Rolf Breinbauer and Matthias Mental -- Sequence specific DNA-binding small molecules for protein recruitment and modulation of transcription / Hans-Dieter Arndt and Sascha Baumann -- G-quadruplex ligands as tools for elucidating c-MYC transcriptional regulation / Barbara Sacca and Markus Kaiser.
520 $aThis first book to adopt a problem-based approach teaches the true basics of the subject by way of everyday case studies. The contributions are presented in a pedagogically uniform and highly motivating fashion, with each chapter introducing a different biological problem taken from lab work.
650 0 $aBiochemistry$xExperiments.
650 0 $aBioactive compounds$xSynthesis.
650 0 $aCombinatorial chemistry.
650 7 $aChemische Biologie$2gnd$0(DE-588)7657972-4
650 7 $aBiochemistry$xExperiments.$2fast$0(OCoLC)fst00831968
650 7 $aCombinatorial chemistry.$2fast$0(OCoLC)fst00868966
650 07 $aChemische Biologie.$2swd
700 1 $aWaldmann, H.$q(Herbert),$eeditor.
700 1 $aJanning, Petra,$eeditor.
856 41 $3Table of contents$uhttp://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=017308229&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
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856 41 $3Table of contents$uhttp://digitool.hbz-nrw.de:1801/webclient/DeliveryManager?pid=2971852&custom_att_2=simple_viewer
856 41 $3Table of contents$uhttp://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017308229&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
856 42 $qtext/html$uhttp://deposit.d-nb.de/cgi-bin/dokserv?id=3191926&prov=M&dok_var=1&dok_ext=htm$3Inhaltstext
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856 4 $qimage/jpeg$uhttp://swbplus.bsz-bw.de/bsz302342575cov.htm$v20090318160342$3Cover
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856 4 $uhttp://digitool.hbz-nrw.de:1801/webclient/DeliveryManager?pid=2971852&custom%5Fatt%5F2=simple%5Fviewer$yChemical biology$3Inhaltsverzeichnis
880 0 $6505-00$aYeast-based chemical genomic approaches / Katja Hübel -- Microarray-based strategies to identify unknown protein interactions / Sabine Borgmann and Christof M. Niemeyer -- Compound collection synthesis for chemical biology / Kamal Kumar -- Target identification and validation of a WNT/β-catenin pathway modulator / Petra Janning -- Activity-based protein profiling of Cys proteases / Renier van der Hoorn -- Use of photoaffinity labeling for the identification of the binding site of the antibiotic linezolid / Rolf Breinbauer and Matthias Mentel -- Surgical strikes : uses of analog sensitive technologies to target kinases of interest / Matthias Rabiller and Daniel Rauh -- Modulation of protein-protein interactions by small molecules / Stefanie Bovens and Christian Ottmann -- Targeted protein degradation in live cells / Markus Kaiser -- Trapoxin B : from total synthesis to epigenetics / Bruno Bulic -- Native chemical ligation : a tool for chemical protein synthesis / Christian F.W. Becker -- Using split inteins to prepare semi-synthetic proteins and to study the mechanism of protein trans-splicing / Henning D. Mootz -- Elucidation of the Ras cycle with semi-synthetic proteins / Luc Brunsveld -- Study of Rab GTPase recycling using semi-synthetic prenylated proteins / Kirill Alexandrov ... [et al.] -- Development of a model cancer vaccine candidate based on the MUC1 cellular surface glycopeptide epitope / Christian Hedberg and Ulrika Westerlind -- The introduction of chemical reporter groups by bioorthogonal ligation reactions for the imaging of cell-surface glycans / Rolf Breinbauer and Matthias Mental -- Sequence specific DNA-binding small molecules for protein recruitment and modulation of transcription / Hans-Dieter Arndt and Sascha Baumann -- G-quadruplex ligands as tools for elucidating c-MYC transcriptional regulation / Barbara Saccà and Markus Kaiser.
852 00 $bsci$hQD415$i.C456 2009