MARC Record from marc_columbia

LEADER: 04303cam a2200649Mi 4500
001 14747596
005 20220501001951.0
006 m o d
007 cr |n|||||||||
008 180116e20170713flu o 000 0 eng d
035 $a(OCoLC)on1066389831
035 $a(NNC)14747596
040 $aWYU$beng$cWYU$dOCLCQ$dTYFRS$dOCLCF$dUKAHL$dOCLCO
020 $a1138105066
020 $a9781138105065
020 $z9781138105065
020 $z1138105066$q(Trade Cloth)
024 3 $a9781138105065
035 $a(OCoLC)1066389831
037 $aK34996$b00004766
050 4 $aQP752$b.A7
082 04 $a612/.01577$223
049 $aZCUA
100 1 $aWillis, A. L.,$eauthor.
240 10 $aCRC Handbook of Eicosanoids, Volume II (Online)
245 10 $aCRC Handbook of Eicosanoids, Volume II :$bProstaglandins and Related Lipids.
260 $aBoca Raton :$bCRC Press LLC$cJuly 2017$aFlorence :$bTaylor & Francis Group [distributor]
300 $a1 online resource (416 pages).
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
490 1 $aCRC Press Revivals Ser.
520 8 $aAnnotation$bBuilding upon the extensive compilation of biochemical data featured in Volume I of the Handbook of Eicosanoids, the new Volume II describes the past, present, and potential future impact of eicosanoid research on new drug development. The reader is taken from a historical perspective through state-of-the-art basic concepts to extensive tabulation of molecular structures of compounds known to act via the eicosanoid system. Much emphasis is given to recent breakthroughs in the mechanism of action of anti-inflammatory corticosteroids and the development of receptor antagonists for prostaglandins and leukotrienes. There is also an introductory chapter that proposes areas that require further investigation and novel approaches using existing technology. This handbook will thus be invaluable for medicinal chemists, pharmacologists, and all those involved in basic research in the eicosanoid area. In addition, many parts of this handbook are suitable for use by university lecturers and students. There are 20 figures and 44 extensive tables as well as a bibliography containing more than 2,000 references that complement the text.
521 $aScholarly & Professional$bCRC Press LLC.
505 00 $t1. Introcution to the area 2.Therapeutic Promise of the Eicosanoid Area: An Overview 3. Inhibitors of Eicosanoid production 4. Antiphospholipase Proteins: Introduction and Overview 5. Effects of Corticosteroids on Release of Eicosanoid Precursors 6. Drugs that Inhibit the Activities or Activation of Phospholipases and Other Acylhydrolases 7. Cyclooxygenase Inhibitors 8. Lipoxygenase Inhibitors 9. Selective Inhibitors of Thromboxane Synthetase 10. Modulators of Eicosanoid actions 11. Classification of Prostanoid Receptors 12. Eicosanoid Receptor Antagonists 13. Leukotriene Antagonists 14. Regulation of Cyclic Nucleotide Metabolism in Human Platelets by Prostanoids 15. Opposite Effects of Prostaglandins on Human Platelets Mediated by Distinct Protein Kinases. Index.
650 0 $aArachidonic acid$xDerivatives$vHandbooks, manuals, etc.
650 0 $aProstaglandins$vHandbooks, manuals, etc.
650 0 $aLeukotrienes$vHandbooks, manuals, etc.
650 6 $aAcide arachidonique$xDérivés$vGuides, manuels, etc.
650 6 $aProstaglandines$vGuides, manuels, etc.
650 7 $aSCIENCE / Chemistry / Organic.$2bisacsh
650 7 $aMEDICAL / Pharmacology.$2bisacsh
650 7 $adrug development.$2bisacsh
650 7 $aeicosanoid research.$2bisacsh
650 7 $amedicinal chemists.$2bisacsh
650 7 $apharmacologists.$2bisacsh
650 7 $abiochemical data.$2bisacsh
650 7 $aArachidonic acid$xDerivatives.$2fast$0(OCoLC)fst00812618
650 7 $aLeukotrienes.$2fast$0(OCoLC)fst00996939
650 7 $aProstaglandins.$2fast$0(OCoLC)fst01079463
655 0 $aElectronic book.
655 4 $aElectronic books.
655 7 $aHandbooks and manuals.$2fast$0(OCoLC)fst01423877
710 2 $aCRC Press LLC.
830 0 $aCRC Press Revivals Ser.
856 40 $uhttp://www.columbia.edu/cgi-bin/cul/resolve?clio14747596$zTaylor & Francis eBooks
852 8 $blweb$hEBOOKS