MARC Record from marc_columbia

LEADER: 06025cam a22006374a 4500
001 15068076
005 20220618231028.0
006 m o d
007 cr cnu---unuuu
008 060711s2005 flua ob 001 0 eng d
010 $a 2004065509
035 $a(OCoLC)ocm70277112
035 $a(NNC)15068076
040 $aN$T$beng$epn$cN$T$dYDXCP$dOCLCQ$dCASUM$dCAI$dHS0$dIDEBK$dE7B$dOCLCQ$dTULIB$dOCLCQ$dUIU$dCRCPR$dOCLCQ$dMND$dOCLCQ$dUAB$dOCLCF$dOCLCO$dOCLCQ$dUKMGB$dOCLCO$dCOO$dWYU$dOCLCA$dVT2$dYDX$dTYFRS$dLEAUB$dUKAHL$dESU$dOCLCO
015 $aGBB7D1786$2bnb
016 7 $a018435795$2Uk
019 $a150374933$a173514602$a276937992$a317753106$a497007612$a647594953$a779915263$a1066004443$a1077295654$a1084324926
020 $a1420027603$q(electronic bk.)
020 $a9781420027600$q(electronic bk.)
020 $z1574444980$q(alk. paper)
020 $z9781574444988$q(alk. paper)
035 $a(OCoLC)70277112$z(OCoLC)150374933$z(OCoLC)173514602$z(OCoLC)276937992$z(OCoLC)317753106$z(OCoLC)497007612$z(OCoLC)647594953$z(OCoLC)779915263$z(OCoLC)1066004443$z(OCoLC)1077295654$z(OCoLC)1084324926
037 $aTANDF_186236$bIngram Content Group
050 4 $aQP625.N89$bN838 2005eb
060 4 $a2005 H-338
060 4 $aQU 57$bN9635 2005
072 7 $aMED$x107000$2bisacsh
082 04 $a611/.01816$222
049 $aZCUA
245 00 $aNucleoside triphosphates and their analogs :$bchemistry, biotechnology, and biological applications /$c[edited by] Morteza M. Vaghefi.
260 $aBoca Raton :$bTaylor & Francis,$c2005.
300 $a1 online resource (393 pages) :$billustrations
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
504 $aIncludes bibliographical references and index.
505 00 $tChemical synthesis of nucleoside 5'-triphosphate /$rMorteza M. Vaghefi --$tEnzymatic synthesis of nucleoside triphosphates /$rStaffan Eriksson --$tSynthesis and properties of NTP analogs with modified triphosphate chains /$rInna Koukhareva, Morteza Vaghefi, and Alexandre Lebedev --$tChemical synthesis of oligonucleotide triphosphates /$rMorteza M. Vaghefi --$tSolid state structures of nucleoside triphosphate metal complexes /$rKatsuyuki Aoki and Ikuhide Fujisawa --$tDNA polymerases and their interactions with DNA and nucleotides /$rAllison A. Johnson, Kevin A Fiala, and Zucai Suo --$tRNA polymerases /$rWissam Abdel-Gawad, Seng-Lai Tan, and Zucai Suo --$tReverse transcriptases /$rLouise Wang and Zucai Suo --$tBase-modified nucleoside triphosphates /$rStephen G. Will and Veeraiah Bodepudi --$tNucleoside triphosphate analogs for nonradioactive labeling of nucleic acids /$rGlenn H. McGall --$tAntiviral drugs /$rErik De Clercq --$tOther drug application /$rJoy Y. Feng and Phillip A. Furman.
588 0 $aPrint version record.
520 8 $aAdenosine triphosphate (ATP), the first nucleoside triphosphate, was discovered in 1929 and synthesized in 1948. Describes as the "universal currency of energy," ATP is essential to cell function in all living things; nucleoside triphosphate was found to be essential to the assembly of DNA. In these 18 papers contributors describe their basic resea$bUsed extensively in cellular and molecular biology research and cytogenetic applications, nucleotide analogs are currently available for the treatment of various diseases. Nucleoside Triphosphate and Their Analogs: Chemistry, Biotechnology, and Biological Applications features the contributions of 18 scientists from both academia and industry in the first complete source dedicated entirely to nucleoside triphosphate (NTP). The text provides collective information on the chemical, physiochemical, and biological properties of both natural and modified NTP alongside their application in life sciences. This book examines the structural components of NTPs' diverse biological properties and therapeutic consequences, including cytotoxic compounds, antiviral agents, and immunosuppressive molecules. The text describes synthetic methods used for all types of nucleotides and reviews families of enzymes that depend on nucleotides for assembling DNA and RNA molecules. This book also emphasizes the key role NTP plays in the global tracking of conformational changes in nucleic acids and nucleic acid complexes and the investigation of cellular processes and genetic material. The author details the pharmaceutical and diagnostic applications of NTP modification and how fluorescent labeled nucleotide analogs provide sensitive probes for studying the structure, dynamics, and interactions of nucleic acids. Nucleoside Triphosphate and Their Analogs: Chemistry, Biotechnology, and Biological Applications discusses the potential of current applications and future research into context with an in-depth analysis of the role anticancer and antiviral nucleoside analogs play in medical treatments, including antiretroviral therapy regimens (for the treatment of HIV), anti-rejection therapy for organ transplants, hematological malignancy therapy, and the treatment of nonmalignant disorders, solid tumors, immunologic diseases, and multiple sclerosis.
650 0 $aNucleotides.
650 0 $aNucleotides$xDerivatives.
650 0 $aAdenosine triphosphate.
650 12 $aNucleotides
650 2 $aAdenosine Triphosphate
650 6 $aNucléotides.
650 6 $aNucléotides$xDérivés.
650 6 $aAdénosine triphosphate.
650 7 $aMEDICAL$xGenetics.$2bisacsh
650 7 $aAdenosine triphosphate.$2fast$0(OCoLC)fst00796573
650 7 $aNucleotides.$2fast$0(OCoLC)fst01041118
655 0 $aElectronic book.
655 4 $aElectronic books.
700 1 $aMonir-Vaghefi, Seyed-Morteza.
776 08 $iPrint version:$tNucleoside triphosphates and their analogs.$dBoca Raton : Taylor & Francis, 2005$z1574444980$w(DLC) 2004065509$w(OCoLC)57311719
856 40 $uhttp://www.columbia.edu/cgi-bin/cul/resolve?clio15068076$zTaylor & Francis eBooks
852 8 $blweb$hEBOOKS