MARC Record from marc_columbia

LEADER: 05249cam a2200745 i 4500
001 15903179
005 20220424000143.0
006 m o d
007 cr cnu---unuuu
008 210830t20222022flua ob 001 0 eng d
035 $a(OCoLC)on1265580096
035 $a(NNC)15903179
040 $aYDX$beng$erda$epn$cYDX$dYDX$dTYFRS$dOCLCO$dYDX$dOCLCO$dOCLCF$dN$T$dOCLCQ$dOCLCO
020 $a1000435369$q(electronic book)
020 $a9781003204091$q(electronic book)
020 $a1003204090$q(electronic book)
020 $a9781000435382$q(electronic book$qEPUB)
020 $a1000435385$q(electronic book$qEPUB)
020 $a9781000435368$q(electronic bk.)
020 $z0367895668$q(hardcover)
020 $z9780367895662$q(hardcover)
035 $a(OCoLC)1265580096
037 $a9781003204091$bTaylor & Francis
050 4 $aQH607$b.R43 2022
072 7 $aSCI$x007000$2bisacsh
072 7 $aSCI$x049000$2bisacsh
072 7 $aMED$x008000$2bisacsh
072 7 $aPSB$2bicssc
082 04 $a571.8/35$223
049 $aZCUA
245 00 $aRedox regulation of differentiation and de-differentiation /$cedited by Carsten Berndt, Christopher Horst Lillig.
264 1 $aBoca Raton, FL :$bCRC Press,$c2022.
264 4 $c©2022
300 $a1 online resource (xii, 380 pages)
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
490 1 $aOxidative stress and disease ;$v48
504 $aIncludes bibliographical references and index.
520 $aCell differentiation and the development of multicellular organisms are processes of self-assembly, controlled and driven by signaling molecules and cascades including redox regulation. These reactions may have provided the energy for the first metabolic steps in the evolution of life. Today, redox modifications are established as important regulatory events in cellular functions including differentiation and development. Redox modifications of single cysteines regulate differentiation of stem cells, formation of functioning organs, and de-differentiation such as formation of cancer cells. Current cancer therapy is based on redox events as well and regeneration often reactivates developmental pathways. Understanding differentiation and de-differentiation on a molecular level is therefore a prerequisite for the continuing development of new medical therapies. This book summarizes the roles of redox regulation in development by bringing together different concepts and comparing similarities and differences between various cell types and species. An international team of contributors presents several new aspects of redox-regulated differentiation and de-differentiation, including aspects of redox medicine. Key Features Provides the first summary on this important topic Reviews redox-dependent development of model organisms and single organs Highlights the redox-regulated pathways important for differentiation processes Illustrates the potential of redox medicine Combines state-of-the-art knowledge in differentiation/development, aging/longevity, and repair/regeneration Written by leading experts in the field Related Titles Ayyanathan, K., ed. Cancer Cell Signaling: Targeting Signaling Pathways Toward Therapeutic Approaches to Cancer (ISBN 978-1-77188-067-1) Clarke, M. & J. Frampton. Stem Cells: Biology and Application (ISBN 9780-8153-4511-4) Lim, W. & B. Mayer. Cell Signaling: Principles and Mechanisms (ISBN 978-0-8153-4244-1) Wong, E., ed. Autophagy and Signaling (ISBN 978-0-367-65772-7)
545 0 $aCarsten Berndt is in the Department of Neurology, Heinrich-Heine-Universitt̃ Düsseldorf. He is the author or co-author of over 50 peer revidewed scholarly publications. His research has focuesd on the essential role of redox regulation in health and disease. Christopher Horst Lillig is at the Institute for Medical Biochemistry and Molecular Biology at the University of Greifswald.
588 0 $aOnline resource; title from digital title page (viewed on September 28, 2021).
650 0 $aCell differentiation.
650 0 $aCellular signal transduction.
650 0 $aOxidation-reduction reaction.
650 2 $aCell Differentiation
650 2 $aSignal Transduction
650 2 $aOxidation-Reduction
650 6 $aCellules$xDifférenciation.
650 6 $aTransduction du signal cellulaire.
650 6 $aOxydoréduction.
650 7 $aSCIENCE$xLife Sciences$xBiochemistry.$2bisacsh
650 7 $aSCIENCE$xLife Sciences$xBiology$xMolecular Biology.$2bisacsh
650 7 $aMEDICAL$xBiochemistry.$2bisacsh
650 7 $aCell differentiation.$2fast$0(OCoLC)fst00850182
650 7 $aCellular signal transduction.$2fast$0(OCoLC)fst00850288
650 7 $aOxidation-reduction reaction.$2fast$0(OCoLC)fst01049564
655 4 $aElectronic books.
700 1 $aBerndt, Carsten,$eeditor.
700 1 $aLillig, Christopher Horst,$eeditor.
776 08 $iPrint version:$z9781000435382
776 08 $iPrint version:$z0367895668$z9780367895662$w(OCoLC)1241730099
830 0 $aOxidative stress and disease.
856 40 $uhttp://www.columbia.edu/cgi-bin/cul/resolve?clio15903179$zTaylor & Francis eBooks
852 8 $blweb$hEBOOKS