MARC Record from marc_columbia

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049 $aZCUA
100 1 $aCarey, Michael$q(Michael F.)
245 10 $aTranscriptional regulation in eukaryotes :$bconcepts, strategies, and techniques /$cMichael Carey, Stephen T. Smale.
260 $aCold Spring Harbor, NY :$bCold Spring Harbor Laboratory Press,$c©2000.
300 $a1 online resource (xxix, 640 pages) :$billustrations
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
347 $adata file$2rda
504 $aIncludes bibliographical references and index.
506 $3Use copy$fRestrictions unspecified$2star$5MiAaHDL
533 $aElectronic reproduction.$b[Place of publication not identified] :$cHathiTrust Digital Library,$d2010.$5MiAaHDL
538 $aMaster and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.$uhttp://purl.oclc.org/DLF/benchrepro0212$5MiAaHDL
583 1 $adigitized$c2010$hHathiTrust Digital Library$lcommitted to preserve$2pda$5MiAaHDL
588 0 $aPrint version record.
505 0 $aA primer on transcriptional regulation in mammalian cells -- Initial strategic issues -- Modes of regulating mRNA abundance -- Transcription initiation site mapping -- Functional assays for promoter analysis -- Identification and analysis of distant control regions -- Identifying cis-acting DNA elements within a control region -- Identification of DNA-binding proteins and isolation of their genes -- Confirming the functional importance of a protein-DNA interaction -- In vivo analysis of an endogenous control region -- Approaches for the synthesis of recombinant transcription factors -- Identifying and characterizing transcription factor domains -- Theory, characterization, and modeling of DNA binding by regulatory transcription factors -- Crude and fractionated systems for in vitro transcription -- Approaches for studying transcription complex assembly.
520 1 $a"In the genome era, the analysis of gene expression has become a critical requirement in many laboratories. But there has been no comprehensive source of strategic, conceptual, and technical information to guide this often complex task. Transcriptional Regulation in Eukaryotes answers that need. Written by two experienced investigators, Michael Carey and Stephen Smale at the UCLA School of Medicine, and based in part on the Gene Expression course taught at Cold Spring Harbor Laboratory, this book directly addresses all the concerns of a laboratory studying the regulation of a newly isolated gene or the biochemistry of a new transcription factor." "This book is essential reading for anyone pursuing the analysis of gene expression in model systems or disease states."--Jacket.
650 0 $aGenetic transcription$vRegulations.
650 0 $aTranscription factors.
650 0 $aGenetic transcription$xRegulations$xResearch$xMethodology.
650 2 $aTranscription, Genetic
650 2 $aGene Expression Regulation
650 2 $aTranscription Factors
650 6 $aTranscription génétique$xRégulation.
650 6 $aFacteurs de transcription.
650 6 $aTranscription génétique$xRégulation$xRecherche$xMéthodologie.
650 7 $aSCIENCE$xLife Sciences$xBiochemistry.$2bisacsh
650 07 $aTranscription factors.$2cct
650 07 $aGenetic transcription$xRegulations$xResearch$xMethodology.$2cct
650 07 $aTranscription, Genetic.$2cct
650 07 $aGene expression regulation.$2cct
650 07 $aTranscription genetique$xRegulation.$2cct
650 07 $aFacteurs de transcription.$2cct
650 07 $aTranscription genetique$xRegulation$xRecherche$xMethodologie.$2cct
650 07 $aGenetic transcription.$2cct
650 7 $aGenetic transcription.$2fast$0(OCoLC)fst00940101
650 7 $aTranscription factors.$2fast$0(OCoLC)fst01154564
650 7 $aEukaryoten$2gnd
650 7 $aGenregulation$2gnd
650 7 $aTranskription$gGenetik$2gnd
650 7 $aTranscription génétique$xCommande, Théorie de la.$2ram
650 7 $aFacteurs de transcription.$2ram
650 7 $aRégulation génétique.$2ram
655 0 $aElectronic book.
655 4 $aElectronic books.
655 7 $aRules.$2fast$0(OCoLC)fst01423857
700 1 $aSmale, Stephen T.
776 08 $iPrint version:$aCarey, Michael (Michael F.).$tTranscriptional regulation in eukaryotes.$dCold Spring Harbor, NY : Cold Spring Harbor Laboratory Press, ©2000$w(DLC) 99049636
856 40 $uhttp://www.columbia.edu/cgi-bin/cul/resolve?clio15923338$zAll EBSCO eBooks
852 8 $blweb$hEBOOKS