MARC Record from Library of Congress

LEADER: 04366cam a22005534a 4500
001 2010007472
003 DLC
005 20110323084258.0
008 100219s2010 sz a b 101 0 eng
010 $a 2010007472
015 $a09,N28,0721$2dnb
015 $a09, N28,0721$2dnb
016 7 $a101524745$2DNLM
016 7 $a994854234$2DE-101
020 $a9783805592437 (hard cover : alk. paper)
020 $a3805592434 (hard cover : alk. paper)
020 $a9783805592444 (eISBN)
020 $a3805592442 (eISBN)
035 $a(OCoLC)ocn529295685
040 $aDNLM/DLC$cDLC$dYDX$dNLM$dOHX$dDEBBG$dYDXCP$dUBY$dHEBIS$dCDX$dDLC
042 $apcc
050 00 $aQH588.S83$bE447 2009
060 00 $a2010 F-608
060 10 $aQU 325$bE49m 2010
082 00 $a616/.02774$222
084 $a610$2sdnb
084 $aWW 8844$2rvk
111 2 $aElse Kröner-Fresenius Symposium on the Molecular Mechanisms of Adult Stem Cell Aging$n(1st :$d2009 :$cGünzburg, Germany)
245 10 $aMolecular mechanisms of adult stem cell aging /$cvolume editor, Karl Lenhard Rudolph.
260 $aBasel :$bKarger,$cc2010.
300 $aviii, 107 p. :$bill. (chiefly col.) ;$c26 cm.
490 1 $aElse Kröner-Fresenius symposia,$x1663-0114 ;$vv. 1
500 $aPapers from the first Else Kröner-Fresenius Symposium on the Molecular Mechanisms of Adult Stem Cell Aging, held in Günzburg, Germany in May 2009.
504 $aIncludes bibliographical references and index.
505 0 $aSpeakers at the Symposium / Hartmann, D. -- Hematopoietic stem cell aging and fate decision / Illing, A., Ju, Z. -- Alterations of systemic environment impair stem cell function during aging / Song, Z., Ju, Z. -- Novel insights into regulation of stem cell aging by aging of the niche and alterations in systemic factors / Geiger, H. -- Aging and hematopoietic malignancies / Gompf, A. -- Intestinal stem cell aging / Sperka, T., Rudolph, K.L. -- Molecular mechanisms of aging in muscle stem cells / Tümpel, S. -- Free radicals and stem cell aging / Guachalla, L.M. -- DNA damage, checkpoint responses, and cell cycle control in aging stem cells / Sperka, T., Nalapareddy, K., Rudolph, K.L.
520 $a"There is growing evidence that adult stem cells age. This process can result in alterations in the number and function of stem cells, leading to distinct phenotypic outcomes in different organ systems. This publication provides an outstanding overview of this emerging field. The molecular causes of stem cell aging remain to be defined. Stem cell aging can involve cell-intrinsic as well as cell-extrinsic alterations affecting the stem cell niche or the macroenvironment. Stem cells have a longer life span than other cell populations and retain a capacity to proliferate and differentiate in adult organs. The aging of adult stem cells plays a key role in the decline of organ maintenance and regenerative potential during aging and during the end stage of chronic diseases. In addition, it can contribute to stem cell transformation and carcinogenesis. Molecular Mechanisms of Adult Stem Cell Aging will appeal to scientists working in the fields such as stem cells, aging, regeneration and cancer. This subject matter should be of interest to physicians and scientists specializing in geriatric medicine, internal medicine, and surgery. It is also likely to be an invaluable resource for medical students and biologists who wish to enhance their understanding of molecular and stem cell biology."--Publisher's description.
650 0 $aStem cells$vCongresses.
650 0 $aCells$xAging$vCongresses.
650 0 $aAging$xMolecular aspects$vCongresses.
650 12 $aAdult Stem Cells$xphysiology$vCongresses.
650 22 $aCell Aging$xgenetics$vCongresses.
650 22 $aDNA Damage$xphysiology$vCongresses.
650 22 $aTelomere$xgenetics$vCongresses.
655 4 $aGünzburg (2009)
655 4 $aKongress.
700 1 $aRudolph, K. Lenhard.
830 0 $aElse Kröner-Fresenius symposia ;$vv. 1.$x1663-0114
856 $uhttp://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=018963037&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA$zInhaltsverzeichnis
856 $uhttp://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=018963037&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA$zKlappentext