MARC Record from Library of Congress

LEADER: 03139cam a22003134a 4500
001 2010015161
003 DLC
005 20141113075241.0
008 100420s2010 nyua b 001 0 eng
010 $a 2010015161
016 7 $a101529186$2DNLM
020 $a9780879698300 (hardcover : alk. paper)
020 $a0879698306 (hardcover : alk. paper)
035 $a(OCoLC)ocn610018850
040 $aDNLM/DLC$cDLC$dYDX$dNLM$dYDXCP$dCDX$dDLC
042 $apcc
050 00 $aRC268.44.P16$bP2 2010
060 10 $aQZ 202$bP999 2010
082 00 $a616.99/4042$222
245 04 $aThe p53 family :$ba subject collection from Cold Spring Harbor Perspectives in biology /$cedited by Arnold J. Levine, David P. Lane.
260 $aCold Spring Harbor, N.Y. :$bCold Spring Harbor Laboratory Press,$cc2010.
300 $aviii, 360 p. :$bill. (chiefly col.) ;$c27 cm.
504 $aIncludes bibliographical references and index.
505 0 $aThe origins and evolution of the p53 family of genes / Vladimir A. Belyi ... [et al.] -- The tumor suppressor p53: from structures to drug discovery / Andreas C. Joerger and Alan R. Fersht -- The isoforms of the p53 protein / Marie P. Khoury and Jean-Christophe Bourdon -- p63 and p73, the ancestors of p53 / Volker Dötsch ... [et al.] -- Transcriptional regulation by p53 / Rachel Beckerman and Carol Prives -- Posttranslational modification of p53: cooperative integrators of function / David W. Meek and Carl W. Anderson -- The regulation of the p53-mediated stress response by MDM2 and MDM4 / Mary Ellen Perry -- Tied up in loops: positive and negative autoregulation of p53 / Xin Lu -- Tp53 mutations in human cancers: origins, consequences, and clinical use / Magali Olivier, Monica Hollstein, and Pierre Hainaut -- Clinical outcomes and correlates of TP53 mutations and cancer / Ana I. Robles and Curtis C. Harris -- Single-nucleotide polymorphisms in the p53 signaling pathway / Lukasz F. Grochola ... [et al.] -- Tumor suppressive functions of p53 / Jack T. Zilfou and Scott W. Lowe -- p53 regulation of metabolic pathways / Eyal Gottlieb and Karen H. Vousden -- p53 regulation of the IGF-1/AKT/mTOR pathways and the endosomal compartment / Zhaohui Feng -- The role of p53 gene family in reproduction / Wenwei Hu -- Using mice to examine p53 functions in cancer, aging, and longevity / Lawrence A. Donehower -- Mutant p53 gain-of-function in cancer / Moshe Oren and Varda Rotter -- Mouse models of p53 functions / Guillermina Lozano -- Zebrafish models of p53 functions / Narie Y. Storer and Leonard I. Zon -- Phylogeny and function of the invertebrate p53 superfamily / Rachael Rutkowski, Kay Hofmann, and Anton Gartner -- P53-based cancer therapy / David P. Lane, Chit Fang Cheok, and Sonia Lain -- Pathologies associated with the p53 response / Andrei V. Gudkov and Elena A. Komarova -- P53 research: the past thirty years and the next thirty years / David Lane and Arnold Levine.
650 0 $ap53 antioncogene.
650 12 $aGenes, p53$vCollected Works.
700 1 $aLevine, Arnold J.$q(Arnold Jay),$d1939-
700 1 $aLane, David,$d1952-
730 0 $aCold Spring Harbor perspectives in biology.