MARC Record from Library of Congress

LEADER: 06293cam a22004097a 4500
001 2012942124
003 DLC
005 20150708081713.0
008 120615s2012 nyua b 001 0 eng
010 $a 2012942124
016 7 $a101592844$2DNLM
020 $a9781617799730 (alk. paper)
020 $a1617799734 (alk. paper)
020 $a9781617799747 (eBook)
020 $a1617799742 (eBook)
035 $a(OCoLC)ocn810866017
040 $aNLM$beng$cNLM$dSIRPL$dCOU$dYDXCP$dBWX$dOCLCO$dDLC
042 $anlmcopyc$alccopycat
050 00 $aTP248.65.I49$bA58 2012
060 00 $aW1$bME9616J v.907 2012
060 10 $aQW 525
245 00 $aAntibody engineering :$bmethods and protocols /$cedited by Patrick Chames.
250 $a2nd ed.
260 $aNew York :$bHumana Press,$cc2012.
300 $axvi, 734 p. :$bill. (some col.) ;$c26 cm.
490 1 $aMethods in molecular biology,$x1064-3745 ;$v907
490 1 $aSpringer Protocols
504 $aIncludes bibliographical references and index.
520 $a"Antibody Engineering: Methods and Protocols, Second Edition was compiled to give complete and easy access to a variety of antibody engineering techniques, starting from the creation of antibody repertoires and efficient ways to select binders from these repertoires, to their production in various hosts, their detailed characterization using various well established techniques, and to the modification and optimization of these lead molecules in terms of binding activity, specificity, size, shape, and more"--Publisher.
505 0 $aUse of IMGT® databases and tools for antibody engneering and humanization / Marie-Paule Lefranc ... [et al.] -- Computer-assisted modeling of antibody variable domains / Oscar H.P. Ramos -- Cloning single-chain antibody fragments (scFv) from hyrbidoma cells / Lars Toleikis and André Frenzel -- Human in-cell scFv library from infiltrating B cell / Sylvie Peraldi-Roux -- Construction of human naive antibody gene libraries / Michael Hust ... [et al.] -- Synthetic customized scFv libraries / Gautier Robin and Pierre Martineau -- Selection of stable scFv antibodies by phage display / Eeva-Christine Brockmann -- Generation of single domain antibody fragments derived from camelids and generation of manifold constructs / Cécile Vincke ... [et al.] -- Generation and isolation of target-specific single-domain antibodies from shark immune repertoires / Mischa Roland ... [et al.] -- Generation of human single domain antibody repertoires by Kunkel mutagenesis / Romain Rouet, Kip Dudgeon, and Daniel Christ -- Phage display and selections on purified antigens / Julie Matz and Patrick Chames -- Phage display and selections on cells / Klervi Even-Desrumeaux and Patrick Chames -- Humanization by CDR grafting and specificity-determining residue grafting / Jin Hong Kim and Hyo Jeong Hong -- Humanization by guided selections / Sang Jick Kim and Hyo Jeong Hong -- Selection of antibody fragments by yeast display / Nathalie Scholler -- Evolution of antibodies in vitro by ribosome display / Bryan M. Edwards and Mingyue He -- Mammalian cell surface display of full length IgG / Chen Zhou and Wenyan David Shen -- Production of antibody fragments in Escherichia coli / Tomohisa Katsuda ... [et al.] -- Production of antibody derivatives in the methylotrophic yeast Pichia pastoris / Steve Schoonooghe, Jannick Leoen, and Jurgen Haustraete -- Monoclonal antibody expression in mammalian cells / Richard Yi Zhang and Wenyan David Shen -- Production of recombinant antibodies in Drosophila melanogaster S2 cells / Daniel X. Johansson, Thomas Krey, and Oskar Andersson -- Production of antibody fragments using the baculovirus-insect cell system / Takanori Furuta, Takafumi Ogawa, and Hideki Yamaji -- Transient and stable expression of antibodies in Nicotiana species / Freydoun Garabagi, Michael D. McLean, and J. Christopher Hall -- Measuring antibody-antigen binding kinetics using surface plasmon resonance / Stephen Hearty, Paul Leonard, and Richard O'Kennedy -- Affinity determination of biotinylated antibodies by flow cytometry / Klervi Even-Desrumeaux and Patrick Chames -- Affinity maturation of antibodies : optimized methods to generate high-quality scFv libraries and isolate IgG candidates by high-throughput screening / Laurence Renaut ... [et al.] -- Affinity maturation by semi-rational approaches / Rodrigo Barderas ... [et al.] -- Molecular scanning : combining random mutagenesis, ribosome display, and bioinformatic analysis for protein engineering / Alfredo Darmanin-Sheehan ... [et al.] -- Fucose-targeted glycoengineering of pharmaceutical cell lines / Christiane Ogorek ... [et al.] -- Fc engineering : design, expression, and functional characterization of antibody variants with improved effector function / Stefanie Derer ... [et al.] -- Fc engineering : serum half-life modulation through FcRn binding / Tove Olafsen -- Monoclonal antibody lead characterization : in vitro and in vivo methods / Axel Hernandez ... [et al.] -- Production, purification, and characterization of scFv TNF ligand fusion proteins / Andrea Fick, Agnes Wyzgol, and Harald Wajant -- Antibody-IL2 fusion proteins for tumor targeting / Andreas A. Hombach and Hinrich Abken -- Recombinant immunotoxins with low endotoxins for clinical and animal studies / Masanori Onda -- Chimeric antigen receptors for T-cell based therapy / Eleanor J. Cheadle ... [et al.] -- Selection and use of intracellular antibodies (intrabodies) / Sandrine Moutel, Clément Nizak, and Franck Perez -- Radiolabeled antibodies for cancer imaging and therapy / Jacques Barbet ... [et al.] -- Design and production of multimeric antibody fragments, focused on diabodies with enhanced and clinical efficacy / Glenn A. Powers, Peter J. Hudson, and Michael P. Wheatcroft -- Production of bispecific antibodies : diabodies and tandem scFv / Nora Hornig and Aline Färber-Schwarz.
650 0 $aImmunotechnology$vLaboratory manuals.
650 12 $aAntibodies$xtherapeutic use$vLaboratory Manuals.
650 22 $aAntibodies$xgenetics$vLaboratory Manuals.
650 22 $aProtein Engineering$xmethods$vLaboratory Manuals.
700 1 $aChames, Patrick.
830 0 $aMethods in molecular biology (Clifton, N.J.) ;$vv. 907.$x1064-3745
830 0 $aSpringer protocols.