MARC Record from Library of Congress

LEADER: 01869nam a22003378a 4500
001 2008029786
003 DLC
005 20080717105526.0
008 080703s2008 nju b 001 0 eng
010 $a 2008029786
020 $a9780470086797 (cloth)
035 $a(DNLM)101478607
040 $aDNLM/DLC$cDLC
042 $apcc
050 00 $aRM301.55$b.N83 2008
060 10 $aQV 38$bN964 2008
082 00 $a615/.7$222
245 00 $aNuclear receptors in drug metabolism /$c[edited by] Wen Xie.
260 $aHoboken, NJ :$bJohn Wiley & Sons,$c2008.
263 $a0901
300 $ap. ;$ccm.
504 $aIncludes bibliographical references and index.
505 0 $aDrug metabolism : significance and challenges -- Establishing orphan nuclear receptors PXR and CAR as xenobiotic receptors -- Nuclear receptor-mediated regulation of phase II conjugating enzymes -- Nuclear receptor-mediated regulation of drug transporters -- Structure and function of PXR and CAR -- Xenobiotic receptor co-factors and co-regulators -- Animal models of xenobiotic nuclear receptors and their utility in drug development -- Nuclear receptors and drug-drug interactions of prescription drugs and herbal medicines -- Genetic variants of xenobiotic receptors and their implications in drug metabolism and pharmacogenetics -- Beyond PXR and CAR : xenobiotic regulation by other nuclear receptors -- The emerging role of retinoid-related orphan receptor (ROR) and its crosstalk with LXR in the regulation of drug metabolizing enzymes.
650 0 $aDrugs$xMetabolism.
650 0 $aNuclear receptors (Biochemistry)
650 0 $aGenetic regulation.
650 12 $aReceptors, Cytoplasmic and Nuclear$xmetabolism.
650 22 $aDrug Delivery Systems$xmethods.
650 22 $aPharmaceutical Preparations$xmetabolism.
650 22 $aReceptors, Steroid$xmetabolism.
700 1 $aXie, Wen,$d1967-