MARC Record from Library of Congress

LEADER: 02946nam a22003138a 4500
001 2009052142
003 DLC
005 20100105094506.0
008 091230s2010 enk b 001 0 eng
010 $a 2009052142
020 $a9780470772744 (cloth)
035 $a(DNLM)101521756
040 $aDNLM/DLC$cDLC
042 $apcc
050 00 $aRC677$b.C365 2010
060 10 $aWG 120$bC26715 2010
082 00 $a616.1/061$222
245 00 $aCardiotoxicity of non-cardiovascular drugs /$ceditor, Giorgio Minotti.
260 $aChichester, West Sussex :$bWiley,$c2010.
263 $a1004
300 $ap. ;$ccm.
504 $aIncludes bibliographical references and index.
505 8 $aMachine generated contents note: List of Contributors -- 1. Mitochondrial Dysfunction In Cell Injury and Cardiotoxicity -- Fabio Di Lisa, Martina Semenzato, Andrea Carpi, Sara Menazza, Nina Kaludercic, Roberta Menabò, Marcella Canton -- 2. Cardiovascular Liabilities of Drugs: Regulatory Aspects -- Claudio Arrigoni -- 3. Cellular Mechanisms, Molecular Targets, and Structure-Function Relationships In Drug-Induced Arrhythmias: The Case Of Antihistamines, Psychoactive Drugs, and Antimicrobial Agents -- Maria Virginia Soldovieri and Maurizio Taglialatela -- 4. Cardiovascular Toxicity of Antitumor Drugs: Dimensions of the Problem in Children -- Rebecca Scully, Louis Pruitt, Steven E. Lipshultz -- 5. Cardiovascular Toxicity of Antitumor Drugs: Dimension of the Problem in Adult Settings -- Joseph R. Carver and Chaitali J. Desai -- 6. Diagnostic Aspects of Cardiovascular Toxicity of Antitumor Drugs -- Michael S. Ewer, Thomas M. Suter -- 7. Cardiovascular Toxicity of Antitumor Drugs: Translating Molecular Mechanisms into Clinical Facts -- Pierantonio Menna, Emanuela Salvatorelli, Carlo Salsano, Luca Gianni*, and Giorgio Minotti -- 8. NSAID Action and the Foundations for Cardiovascular Toxicity -- Anna L. Blobaum and Lawrence J. Marnett -- 9. Cardiovascular toxicities of NSAIDS: Epidemiologic aspects -- Antonio González-Pe;rez, Luis Alberto Garci;a Rodriguez -- 10. Cardiovascular Toxicities of Life-Saving Drugs: Antiviral Therapy -- James J. Kohler & William Lewis.
520 $a"First book to deal with this important area of adverse drug reactions -- cardiotoxicity is one of the major forms of toxicity seen in drugs and it accounts for most drug recalls and delays experienced in regulatory approvals. Covers four important therapeutic classes: psychoactive drugs; anticancer drugs; non-steroidal anti-inflammatory drugs; and anti-retroviral drugs. - Emphasis on the preclinical screening of drug cardiotoxicity, to enable drug developers to test for this toxicity before starting expensive clinical trials"--Provided by publisher.
650 0 $aCardiovascular toxicology.
650 12 $aCardiovascular Diseases$xchemically induced.
650 22 $aCardiovascular System$xdrug effects.
650 22 $aDrug Toxicity.
700 1 $aMinotti, Giorgio.