MARC Record from Library of Congress

LEADER: 01607cam a22003498a 4500
001 2009028151
003 DLC
005 20100623165056.0
008 090709s2010 flu b 001 0 eng
010 $a 2009028151
020 $a9781420070996 (hardcover : alk. paper)
035 $a(DNLM)101510192
040 $aDNLM/DLC$cDLC
042 $apcc
050 00 $aRM301.42$b.M37 2010
060 10 $aQV 744$bM383q 2010
082 00 $a615/.19$222
100 1 $aMartin, Yvonne Connolly,$d1936-
245 10 $aQuantitative drug design :$ba critical introduction /$cYvonne C. Martin.
250 $a2nd ed.
260 $aBoca Raton, FL :$bTaylor & Francis,$cc2010.
263 $a0909
300 $ap. ;$ccm.
504 $aIncludes bibliographical references and index.
505 0 $aOverview of quantitative drug design -- Noncovalent interactions in biological systems -- Preparation of 3D structures of molecules for 3D QSAR -- Calculating physical properties of molecules -- Biological data -- Form of equations relating potency and physical properties -- Statistical basis of regression and partial least-squares analysis -- Strategy for the statistical evaluation of a data set of related molecules -- Detailed examples of QSAR calculations on erythromycin esters -- Case studies -- Methods to approach other structure-activity problems.
650 0 $aDrugs$xStructure-activity relationships.
650 0 $aQSAR (Biochemistry)
650 0 $aDrugs$xDesign.
650 12 $aDrug Design.
650 22 $aBiopharmaceutics.
650 22 $aModels, Theoretical.
650 22 $aQuantitative Structure-Activity Relationship.