MARC Record from Library of Congress

LEADER: 02540cam a22003974a 4500
001 2010043286
003 DLC
005 20111222101547.0
008 101015s2011 njua b 001 0 eng
010 $a 2010043286
016 7 $a101544260$2DNLM
020 $a9780470449820 (cloth)
020 $a0470449829 (cloth)
020 $a9781118001042 (oBook)
020 $a1118001044 (oBook)
020 $a9781118008980 (ePub)
020 $a1118008987 (ePub)
035 $a(OCoLC)ocn671385938
040 $aDNLM/DLC$cDLC$dYDX$dNLM$dYDXCP$dCDX$dDLC
042 $apcc
050 00 $aRA1224.3$b.A679 2011
060 00 $a2011 J-266
060 10 $aQV 38
082 00 $a616/.042$222
245 00 $aApplications of toxicogenomics in safety evaluation and risk assessment /$cedited by Darrell R. Boverhof, B. Bhaskar Gollapudi.
260 $aHoboken, N.J. :$bJohn Wiley & Sons,$cc2011.
300 $axiii, 377 p. :$bill. (some col.) ;$c25 cm.
504 $aIncludes bibliographical references and index.
505 0 $aToxicology, "omics" technologies, and toxicogenomics : a primer -- Introduction to human health risk assessment -- Practical considerations for the application of toxicogenomics to risk assessment -- early experience, current drivers, and a path forward -- Approaches and practical considerations for the analysis of toxicogenomics data -- Genomics in identifying mutagenic mode of action in carcinogenesis -- Application of genomics for predicting and understanding the mode of action for non-genotoxic carcinogens -- Genomics in characterizing endocrine toxicity -- Studying organ specific toxicity using gene expression profiling -- Toxicogenomic studies in human populations -- Toxicogenomics applied to ecological risk assessment -- Analysis of transcriptomic dose response data for toxicology and risk assessment -- Toxicogenomics as a tool for validating animal to human extrapolations in chemical risk assessment: concepts, applications and challenges -- Toxicogenomics and animal alternatives -- Toxicogenomics and the regulatory framework -- Standardization of gene expression information for the safety evaluation -- activities in Japan -- Applying transcriptional profiling in drug safety evaluation -- Reframing the risk assessment paradigm : towards a systems biology approach.
650 0 $aGenetic toxicology.
650 0 $aToxicity testing.
650 0 $aHealth risk assessment.
650 12 $aToxicogenetics.
650 22 $aRisk Assessment.
700 1 $aBoverhof, Darrell R.
700 1 $aGollapudi, B. Bhaskar.