MARC Record from Library of Congress

LEADER: 03490cam a22003734a 4500
001 2011023852
003 DLC
005 20120719094514.0
008 110706s2012 nyua b 001 0 eng
010 $a 2011023852
016 7 $a015993748$2Uk
020 $a9781936113064 (hardcover : alk. paper)
020 $a1936113066 (hardcover : alk. paper)
035 $a(OCoLC)ocn642844743
040 $aDLC$cDLC$dYDX$dBTCTA$dYDXCP$dSCB$dUKMGB$dCDX$dAGL$dUAF$dDLC
042 $apcc
050 00 $aQP551$b.P69594 2012
070 0 $aQP551$b.P69594 2012
082 00 $a572/.64$223
245 00 $aProtein homeostasis /$cedited by Richard I. Morimoto, Dennis J. Selkoe, Jeffery W. Kelly.
250 $a1st ed.
260 $aCold Spring Harbor, N.Y. :$bCold Spring Harbor Laboratory Press,$cc2012.
300 $aviii, 349 p. :$bill. (some col.) ;$c26 cm.
490 1 $aCold Spring Harbor perspectives in biology
500 $a"A subject collection from Cold Spring Harbor Perspectives in biology."
504 $aIncludes bibliographical references and index.
505 0 $aI. Chemistry and biology of proteostasis -- Physical biochemistry of protein folding and misfolding / Michele Vendruscolo, Tuomas P. J. Knowles, and Christopher M. Dobson -- Integrating protein homeostasis strategies in prokaryotes / Axel Mogk, Damon Huber, and Bernd Bukau -- Cellular strategies of protein quality control / Bryan Chen, Marco Retzlaff, Thomas Roos, and Judith Frydman -- Integration of clearance mechanisms: the proteasome and autophagy / Esther Wong and Ana Maria Cuervo -- Aging as an event of proteostasis decline / Rebecca C. Taylor and Andrew Dillin -- The stress of protein misfolding: from single cells to multicellular organisms / Tali Gidalevitz, Veena Prahlad, and Richard I. Morimoto -- II. Protein quality control in cellular compartments -- Protein folding in the cytoplasm and the heat shock response / Martin Vabulas, Swasti Raychaudhuri, Manajit Hayer-Hartl, and F. Ulrich Hartl -- Protein folding and quality control in the ER / Kazutaka Araki and Kazuhiro Nagata -- Stress and its functional link to mitochondria: role in cell survival and death / Jyoti D. Malhotra and Randy Kaufman -- Quality control of mitochondrial proteostasis / Michael J. Baker, Takashi Tatsuta, and Thomas Langer -- III. Disorders of protein homeostasis -- Hepatic fibrosis and carcinogenesis in alpha-1-antitrypsin deficiency: a prototype for chronic tissue damage in gain-of-function disorders / David H. Perlmutter and Gary A. Silverman -- Alzheimer disease / Dennis J. Selkoe -- Huntington's disease / Steven Finkbeiner -- Proteostasis and movement disorders: Parkinson's disease and amyotrophic lateral sclerosis / Daryl A. Bosco, Matthew J. LaVoie, Gregory A. Petsko, and Dagmar Ringe -- Prions / David W. Colby and Stanley B. Prusiner -- Emergent properties of proteostasis in managing cystic fibrosis / William E. Balch, Daniela Roth, and Darren M. Hutt -- Protein misfolding and retinal degeneration / Radouil Tzekov, Linda Stein, and Shalesh Kaushal -- Chemical and Biological approaches for adapting proteostasis to ameliorate protein misfolding and aggregation diseases - progress and prognosis / Susan L. Lindquist and Jeffery W. Kelly.
650 0 $aProteins$xMetabolism.
650 0 $aHomeostasis.
650 0 $aBiological transport.
700 1 $aMorimoto, Richard I.,$d1952-
700 1 $aSelkoe, Dennis J.
700 1 $aKelly, Jeffery W.
830 0 $aCold Spring Harbor perspectives in biology.