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Table of Contents
DNA diagnostics and exon skipping / Umasuthan Srirangalingam and Shern L. Chew
Bioinformatics and mutations leading to exon skipping / F.O. Desmet and C. Béroud
Minigenes to confirm exon skipping mutations / Lourdes R. Desviat, Belén Pérez, and Magdalena Ugarte
Analysis and interpretation of RNA splicing alterations in genes involved in genetic disorders / Maaike P.G. Vreeswijk and Heleen M. van der Klift
Exon skipping mutations in neurofibromatosis / Emanuele Buratti and Diana Baralle
Overview on applications of antisense-mediated exon skipping / Willeke M.C. van Roon-Mom and Annemieke Aartsma-Rus
Overview on DMD exon skipping / Annemieke Aartsma-Rus
Overview on AON design / Annemieke Aartsma-Rus
Optimizing RNA/ENA chimeric antisense oligonucleotides using in vitro splicing / Yasuhiro Takeshima, Mariko Yagi, and Masafumi Matsuo
Optimizing antisense oligonucleotides using phophorodiamidate morpholino oligomers / Linda J. Popplewell, Alberto Malerba, and George Dickson
Optimizing splice-switching oligomer sequences using 2'-O-methyl phosphorothioate chemistry / Carl Adkin, Sue Fletcher, and Steve D. Wilton
Exon skipping quantification by real-time PCR / Alessandra Ferlini and Paola Rimessi
Antisense-mediated exon skipping to shift alternative splicing to treat cancer / Jing Wan
Antisense-mediated exon skipping to generate soluble receptors / A. Seda Yilmaz-Elis and J. Sjef Verbeek
Antisense-mediated exon skipping to reframe transcripts / Sandrina Turczynski ... [et al.]
U1 snRNA as an effective vector for stable expression of antisense molecules and for the inhibition of the splicing reaction / Julie Martone, Fernanda Gabriella De Angelis, and Irene Bozzoni
Engineering U7snRNA gene to reframe transcripts / Aurélie Goyenvalle
Dynamic fluorescent and luminescent reporters for cell-based splicing screens / Claude C. Warzecha, Ruben Hovhannisyan, and Russ P. Carstens
Antisense-mediated exon-skipping to induce gene knockdown / Petra Disterer and Bernard Khoo
Antisense-mediated exon inclusion / Yimin Hua and Adrian R. Krainer
Antisense genes to induce exon inclusion / Rachel Nlend Nlend and Daniel Schümperli
Using mini-genes to identify factors that modulate alternative splicing / Robert Morse, Adrian G. Todd, and Philip J. Young
Overview of alternative oligonucleotide chemistries for exon skipping / Amer F. Saleh, Andrey A. Arzumanov, and Michael J. Gait
Identification of peptides for tissue-specific delivery / Hans Heemskerk
Systemic delivery of antisense oligomer in animal models and its implications for treating DMD / Qi Long Lu and Bo Wu
Cell-penetrating peptides enhance systemic delivery of antisense morpholino oligomers / Hong M. Moulton
Optimizing tissue-specific antisense oligonucleotide-peptide conjugates / Corinne A. Betts ... [et al.]
Edition Notes
Includes bibliographical references and index.
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