Parameters for pesticide QSAR and PBPK/PD models for human risk assessment

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Parameters for pesticide QSAR and PBPK/PD mod ...
James B. Knaak, Charles Timcha ...
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August 3, 2020 | History

Parameters for pesticide QSAR and PBPK/PD models for human risk assessment

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Publish Date
Language
English

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Edition Availability
Cover of: Parameters for pesticide QSAR and PBPK/PD models for human risk assessment
Parameters for pesticide QSAR and PBPK/PD models for human risk assessment
2012, American Chemical Society
in English

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Book Details


Table of Contents

Parameters for pesticide QSAR and PBPK/PD models to inform human risk assessments
Chiral chemistry and toxicity assessments for pyrethroid pesticides
Direct chiral separation of pyrethroid isomers by HPLC with chiral stationary phases
Biotransformation and enzymes responsible for metabolism of pyrethroids in mammals
Characterization of potential age-related differences in pyrethroid pharmacokinetics
15 factors of percutaneous penetration of pesticides
Percutaneous absorption of pesticide formulations
Human metabolic interactions of pesticides : inhibition, induction and activation
Paraoxonase 1 (PON1) status in risk assessment for organophosphate exposure and pharmacokinetics
Carboxylesterases : a multifunctional enzyme involved in pesticide and lipid metabolism
Behavioral changes in adult and young rats as indications of cholinesterase inhibition
Comparison of esterase sensitivity, metabolic efficiency, and toxicity levels of two organophosphorus insecticides, parathion and chlorpyrifos
Regional brain dosimetry for the organophosphorus insecticide chlorpyrifos in the preweanling rat
Pyrethroid actions on sodium channels : isoform and species specificity
In vitro and in vivo experimental data for development and use of pharmacokinetic models for in vitro to in vivo extrapolation of pyrethroid insecticides
In silico strategies for modeling stereoselective metabolism of pyrethroids
Quantitative structure-activity relationships for organophosphate enzyme inhibition
Computational approaches for developing informative prior distributions for bayesian calibration of PBPK models
Use of cytochrome P450-specific parameters and human biomarker data to develop a human physiologically based pharmacokinetic/pharmacodynamic model for dermal chlorpyrifos exposure
Use of in vitro data in PBPK models : an example of in vitro to in vivo extrapolation with carbaryl.

Edition Notes

Includes bibliographical references and index.

Published in
Washington, DC
Series
ACS symposium series -- 1099, ACS symposium series -- 1099.

Classifications

Dewey Decimal Class
615.9/02
Library of Congress
WA 240

The Physical Object

Pagination
p. ;

ID Numbers

Open Library
OL25384782M
ISBN 13
9780841226456
LCCN
2012026986

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August 3, 2020 Edited by ImportBot import existing book
July 25, 2012 Created by LC Bot import new book