When America's nonhuman citizens need help, there's only one place to turn: Project Skin Horse. Headed by Gavotte, a swarm of prim and occasionally angry bees, and staffed by canine field commander Sweetheart, zombie field destroyer Unity, clockwork receptionist Moustachio, transport cyborg Nick, and psychologist and former Army captain Tip Wilkin, Skin Horse is the hardest working social services agency the shadow government has to offer.

Volume 1 is a compilation of the webcomic's first four stories, spanning January 2008 through February 2009: "Cowardly Lion," "Borrowers," "Wild Things," and "I Can Fly." It also includes one bonus story and a selection of fan art.