Historical aspects. Biological actions of calcium / Andrew Fielding Huxley. Professor Ebashi's journey toward the discovery of troponin: a personal recollection / Makoto Endo. Highlights of the history of calcium regulation of striated muscle / John Gergely

Regulation by troponin and tropomyosin. Troponin: structure, function and dysfunction / Iwao Ohtsuki. From the crystal structure of troponin to the mechanism of calcium regulation of muscle contraction / Yuichiro Maeda, Yasushi Nitanai and Toshio Oda. Ca ion and the troponin switch / Maia V. Vinogradova ... [et al.] Disposition and dynamics: interdomain orientations in troponin / Ryan M.B. Hoffman and Brian D. Sykes. Structural basis for calcium-regulated relaxation of striated muscles at interaction sites of troponin with actin and tropomyosin / Kenji Murakami ... [et al.] Tropomyosin: regulator of actin filaments / Sarah E. Hitchcock-DeGregori, Norma J. Greenfield and Abhishek Singh. Tropomyosin and troponin cooperativity on the thin filament / Sabrina E. Boussouf and Michael A. Geeves. Conformational changes in reconstituted skeletal muscle thin filaments observed by fluorescence spectroscopy / Masao Miki. Calcium structural transition of troponin in the complexes, on the thin filament, and in muscle fibres, as studied by site-directed spin-labelling EPR / Toshiaki Arata ... [et al.] Crystal structures of troponyosin: flexible coiled-coil / Yasushi Nitanai ...[et al.] C. elegans model for studying tropomyosin and troponin regulations of muscle contraction and animal behavior / Hiroaki Kagawa ... [et al.] Structural and functional analysis of troponins from scallop striated and human cardiac muscles / Fumiaki Yumoto and Masaru Tanokura

Regulation in cardiac muscle and disorders. Cooperativity in the regulation of force and the kinetics of force development in heart and skeletal muscles / Daniel P. Fitzsimons and Richard L. Moss. Heart failure, ischemia/reperfusion injury and cardiac troponin / R. John Solaro and Grace M. Arteaga. Troponin mutations in cardiomyopathies / Jens Mogensen. Molecular pathogenic mechanisms of cardiomyopathies caused by mutations in cardiac troponin T / Sachio Morimoto. Cardiac troponin levels as a preferable biomarker of myocardial cell degradation / Teruhiko Toyo-oka and Hiroyuki Kumagai

Regulation by myosin. Regulation by myosin: how calcium regulates some myosins, past and present / Andrew G. Szent-Györgyi. Calcium inhibition of physarum myosin as examined by the recombinant heavy mero-myosin / Hozumi Kawamichi ... [et al.]

Excitation-contraction coupling and disorder. Calcium-induced release of calcium from the sarcoplasmic reticulum / Makoto Endo. Dysregulation of the gain of CICR through ryanodine receptor1 (RYR1): the putative mechanism underlying malignant hyperthermia / Yasuo Ogawa. Ion pumping by calcium ATPase of sarcoplasmic reticulum / Chikashi Toyoshima. Regulation of cell functions by Ca2+ oscillation / Masamitsu Iino

Molecular mechanisms of muscle contraction. Evidence about the structural behaviour of myosin crossbridges during muscle contraction / Hugh E. Huxley. Structural alterations of thin actin filaments in muscle contraction by synchrotron x-ray fiber diffraction / Katsuzo Wakabayashi ... [et al.] Regulation of muscle contraction by Ca2+ and ADP: focusing on the auto-oscillation (SPOC) / Shin'ichi Ishiwata ... [et al.] Muscle contraction mechanism based on actin filament rotation / Toshio Yanagida. On the walking mechanism of linear molecular motors / Kazuhiko Kinosita, Jr. ... [et al.] Modeling of the F-actin structure / Toshio Oda ... [et al.]