A blackout brought on by a Mad Dog binge that ended with a self-inflicted steak knife wound bought Bruno Dante another stint in the nuthouse, no different from all the rest. Now it's done, and his wife, Agnes—taking time off from her personal-trainer lover—has come to pick Bruno up and to deliver a message from the West Coast: his screenwriter father is in the hospital in a coma and is not expected to live. So Bruno heads back to Los Angeles for a fraught family reunion, where the tension and stress force him to dull the pain the only way he knows how—with alcohol. And when he wakes up naked in a stolen car with an underage hooker whose pimp has stolen his wallet, Bruno realizes the trip has just begun.