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Describes the synergistic interactions that occur among intrathoracic and CNS feedback loops to permit precise control of regional cardiac behavior. On this basic science foundation, subsequent clinical chapters explore the remodeling that occurs in this system with aging, with the evolution of specific cardiac pathologies, and with the psychological concomitants of heart disease. Most importantly, these chapters provide unique insights into how specific therapies like beta-andrenergic receptor blockade not only affect cardiomyocytes directly but also mitigate the adverse neurohumoral changes that accompany disease processes, such as heart failure and essential hypertension. The paradigm advanced in this volume is that heart disease is a multifaceted phenomenon involving the interplay of neurohumoral, cardiomyocyte and structural elements, each of which depends on the other.
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Subjects
Herzfunktion, Manifestations cardiaques des maladies, Heart, Innervation, Neurotransmitter Agents, Complications et sequelles, Physiopathologie, Neurologie, Appareil cardiovasculaire, Complications, Cardiological manifestations of general diseases, Cardiovascular system, C¿ur, Diseases, Physiopathology, Autonomic Nervous System, Maladies, Physiology, Pathophysiology, Manifestations neurologiques des maladies, Neurologic manifestations of general diseases, Cardiovascular System, Heart, innervation, Heart, physiology, Nervous system, autonomic, Neurotransmitters, Physiology, pathologicalShowing 1 featured edition. View all 1 editions?
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Basic and Clinical Neurocardiology
April 8, 2004, Oxford University Press, USA, Oxford University Press
Hardcover
in English
0195141296 9780195141290
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