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"This book focuses on the rationale of choosing the noninferiority (NI) margin as a small fraction of the therapeutic effect of the active control in a clinical trial. It discusses issues of estimating the effect size based on historical placebo control trials of the active control. The book also covers basic concepts related to NI trials, such as essay sensitivity, constancy assumption, discounting, and preservation. Other topics described include patient populations, three-arm trials, and testing equivalence of three or more groups"--Provided by publisher.
Publish Date
2015
Publisher
Taylor & Francis/CRC Press,
Chapman and Hall/CRC
Language
English
Pages
190
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Edition | Availability |
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1
Noninferiority Testing in Clinical Trials
2020, Taylor & Francis Group, Routledge, Chapman and Hall/CRC
in English
0367576023 9780367576028
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2
Noninferiority testing in clinical trials: issues and challenges
2015, Taylor & Francis/CRC Press, Chapman and Hall/CRC
in English
1466561491 9781466561496
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3
Noninferiority Testing in Clinical Trials
2014, Taylor & Francis Group
in English
1322635803 9781322635804
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4
Noninferiority Testing in Clinical Trials: Issues and Challenges
2014, Taylor & Francis Group
in English
0429071140 9780429071140
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zzzz
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5
Noninferiority Testing in Clinical Trials: Issues and Challenges
2014, Taylor & Francis Group
in English
1466561505 9781466561502
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Book Details
Edition Notes
Includes bibliographical references and index.
Classifications
The Physical Object
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