The volume describes the worldwide state of the HIV/AIDS epidemic and possible ways forward. Marking the 30 years of AIDS, the report takes stock of the changes occurred in the AIDS epidemic and responses since the condition was first diagnosed in 1981. It also features commentaries from 15 leaders in the global AIDS response, including South Africa's President Jacob Zuma, former United States President Bill Clinton, former President of Brazil Luiz Inácio Lula da Silva, singer Angelique Kidjo and former UN Secretary-General Kofi Annan. It covers a wide range of areas, including the results achieved by HIV prevention efforts, the record number of people starting lifesaving treatment and the decline in resources for HIV. It also draws attention to the significant challenges remaining such as the gender inequalities and the increasing HIV prevalence among key populations at higher risk of infection.