Consists of a summary of the constitution, duties, details of work and organisation of the Board, a general review of the year (Walter Eickhoff, G. A. Powell), a statement submitted to the Royal Commission on London Government, a list of managers and officers, statistical tables, a report on the otological work done at the North-Eastern and Western fever hospitals (T. B. Layton), report on the laboratory work and preparation of diphtheria antitoxin carried out under the Board during 1921 (G.E. Cartwright Wood), report on ophthalmia in the Board's hospitals (L. J. Pisani).