The year is 1546 (5306), and due to the inquisition, twelve-year-old Esperanza finds herself suddenly separated from her father, her only family. Her spirit and steadfast faith propel her forward as she finds loving friends who join her in her quest to explore life and her Jewish heritage. Meanwhile, in Constantinople, Esperanza's father, Don Raphael, is tormented by grief over the uncertain fate of his only child. Follow Don Raphael through daring adventures and harrowing journeys as he travels to Aleppo and Italy, meeting many great people along the way. He forges a new life for himself, hoping against hope that he may one day be reunited with his beloved daughter Esperanza.