A failed paramilitary assault on a nest of vampires gives a group of monster hunters called the Blackguards a terrifying glimpse of how deadly the bloodsuckers really are. Now, hunted by the ones they failed to kill and on the run from the law, they're forced to puzzle together the mystery of a strange carcass from colonial times that their ruthless billionaire nemesis will stop at nothing to possess. With one of their own bitten and mutating into a deadly creature of the night, they race against time as they travel the back roads of the Carolinas in a desperate attempt to save her life. But their journey toward salvation will lead to darker places than they ever could have imagined.