As noted in Biowar: The Nixon Administration's Decision to End U.S. Biological Warfare Programs, public attention has become intensely focused upon the threat of attack by biological agents, as the continuing reports of anthrax-contaminated mail facilities and congressional offices appear in the news. The effort to determine who sent the anthrax-laced letters, how they have managed to become so widely dispersed, and to come to grips with the health threat posed have revealed the uncertainties surrounding any such outbreak. These uncertainties regarding the cause, pathology and vectors of an anthrax outbreak are mirrored in the case of the most deadly anthrax epidemic known, which occurred at a Soviet biological weapons facility located in Sverdlovsk (now Ekaterinberg, Russia) in 1979, where at least 68 people died. This incident was a focus of intense controversy and heated exchanges between Washington and Moscow during the 1980s, which would only come to a conclusion with the end of the Soviet Union and a more open Moscow leadership in the 1990s. Still, the heritage of the Soviet biological warfare effort, which was unparalleled in scope and potential lethality, remains a problem today and tomorrow. The documents provided here give a unique perspective on the Sverdlovsk anthrax issue as it unfolded and the questions it provoked, which remain relevant today.