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1
Approaches to the Conformational Analysis of Biopharmaceuticals
2017, Taylor & Francis Group
in English
1138114944 9781138114944
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2
Approaches to the conformational analysis of biopharmaceuticals
2010, CRC Press/Taylor & Francis
in English
1439807809 9781439807804
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3
Approaches to the Conformational Analysis of Biopharmaceuticals
2010, Taylor & Francis Group
in English
1282495623 9781282495623
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4
Approaches to the Conformational Analysis of Biopharmaceuticals
2009, Taylor & Francis Group
in English
1439807817 9781439807811
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5
Approaches to the Conformational Analysis of Biopharmaceuticals
2009, Taylor & Francis Group
in English
0429130872 9780429130878
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Book Details
Table of Contents
Introduction to biopharmaceutical conformational analysis : issues and methods
Comparability of biotechnological/biologic products and biological generics
Application of native electrophoresis for the study of protein conformation
Affinity chromatography including hydrophobic interaction chromatography in the study of biopolymer conformation
Size-exclusion chromatography and bimolecular conformation
The use of analytical ultracentrifugation to study biomolecular conformation
Use of differential scanning calorimetry to measure conformational change in proteins and other biomacromolecules
Light scattering and biomacromolecular conformation
Use of luminescence to measure conformational change in biopharmaceuticals with emphasis on protein and protein drug products
Near-infrared (NIR) spectroscopy and macromolecular conformation
The use of mid-infrared and Fourier transform infrared (FTIR) spectroscopy to study biomacromolecule conformation
The use of Raman spectroscopy to evaluate biopharmaceutical conformation
The use of UV-VIS spectrophotometry for the characterization of biopharmaceutical products
The use of optical rotatory dispersion and circular dichroism to study therapeutic biomacromolecule conformation
The use of nuclear magnetic resonance for the characterization of biotherapeutic products
Use of chemical probes for the study of protein conformation
The use of hydrogen exchange in the study of biopharmaceutical conformation
Use of chemical modification for the conformational analysis of biopharmaceuticals
The use of immunology to characterize biopharmaceutical conformation
The use of limited proteolysis to study the conformation of proteins of biotechnology interest
Other technologies for the characterization of conformational change in biopharmaceuticals
Development of an experimental approach for the study of the conformation of a biological therapeutic product.
Edition Notes
Includes bibliographical references and index.
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