"There is growing evidence that chronic depression is primarily a physical disease and should be treated like one. This program sheds much-needed light on vulnerability to depression, the subtle symptoms of the disease, and treatments involving psychotherapy and antidepressants such as SSRIs. Brain biochemistry and the serotonin transporter promoter gene are discussed as well, and stories of everyday people grappling with the illness express what it feels like to be clinically depressed--and through treatment, the sensation of finding joy and balance seeping back into life."--Container.