In a frenzied rage, the medium, Cara Noma, lunges toward Kay Tracey. "No one can sneer at my power," she cries with an evil look. "I transfer the Green Cameo curse to you!" Kay does not believe a word of it. Kay warns Mrs. Wong about the racket of scheming Cara Noma and thinks the dainty Oriental lady will take her advice. But the medium has other plans.

From that time on, the young detective's footsteps are dogged by misfortune. Trouble also comes to Lotus Gardens, the estate of Mr. and Mrs. Wong, when their beautiful daughter, a bride-to-be, disappears. Although Wilma and Betty Worth, Kay's best friends, entreat her to be extra cautious, Kay feels it her duty to solve the complex case. This becomes very difficult because of the constant interference of jealous Ethel Eaton.

But Kay will not give up. The Green Cameo is a good clue to the whereabouts of the missing girl. Kay finds herself plunged into a hornet's nest of lawbreakers who vow she will never escape to tell the tale.