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"Therapeutic applications of quadruplex nucleic acids provides a single comprehensive survey that describes and assesses recent advances in quadruplex therapeutics and targeting strategies. It also covers the underlying fundamentals of such topics as quadruplex structure, small-molecule recognition, biological roles of genomic quadruplexes, and quadruplex informatics"--P. [4] of cover.
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Therapeutic applications of quadruplex nucleic acids
2012, Elsevier/Academic Press
in English
- 1st ed.
0123751381 9780123751386
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Book Details
Table of Contents
Introduction: quadruplexes and their biology
DNA and RNA quadruplex structures
The structures of human telomeric DNA quadruplexes
Telomeric quadruplex ligands I: anthraquinones and acridines
Telomeric quadruplex ligands II: polycyclic and non-fused ring compounds
The biology and pharmacology of telomeric quadruplex ligands
Genomic quadruplexes as therapeutic targets
RNA quadruplexes
Design principles for quadruplex-binding small molecules
The determination of quadruplex structures.
Edition Notes
Includes bibliographical references and index.
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- Created December 28, 2011
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December 12, 2022 | Edited by MARC Bot | import existing book |
October 12, 2020 | Edited by MARC Bot | import existing book |
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August 2, 2020 | Edited by ImportBot | import existing book |
December 28, 2011 | Created by LC Bot | Imported from Library of Congress MARC record |