An edition of Pharmaceutical Pharmacology
(2009)
Pharmaceutical Pharmacology
by S. C. Mehta and Ashutosh Kar
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Book Details
Table of Contents
Cover; Preface; Contents; Part A; [l] General Pharmacology; Chapter 1. Introduction to Pharmacology; 1.1 Preamable; 1.2 Terminologies; 1.3 History of Medicinal Drug Substances; 1.3.1 Modern Age Drugs; 1.3.2 American Pharmacology; 1.3.3 Twentieth Century Pharmacology; 1.3.4 Pharmacology Practice as to Date; Chapter 2. Sources of Drugs; 2.1 Preamble; 2.2 Classification; 2.2.1 Plant Origin; 2.2.2 Animal Origin; 2.2.3 Microorganism Origin; 2.3 Minerals; 2.4 Synthetic Drugs; 2.5 Recombinant Biotechnology Drugs; 2.5.1 Interferon Alfa-2a, Recombinant; 2.5.2 Lispro Insulin [Syn. Humalog.
Human Insulin Analog]Chapter 3. Dosage Forms and Routes of Drug Administration; 3.1 Introduction; 3.2 Common Dosage Forms; 3.3 Routes of Drug Administration; 3.3.1 Enteral [or Oral Route]; 3.3.2 Parenteral [or Injectional Route]; 3.4 Miscellaneous Routes of Drug Administration; 3.4.1 Sublingual; 3.4.2 Rectal; Chapter 4. Absorption, Distribution, Metabolism and Excretion [ADME} of Drugs; 4.1 Introduction; 4.2 Absorption of Drugs; 4.2.1 Passage of a Drug from GIT; 4.2.2 Effect of pH on Drug Absorption; 4.2.3 Physical Characteristic Factors Influencing Absorption.
4.2.4 Techniques to Delay Absorption of Drugs4.2.5 Accelerating the Rate of Absorption of Drugs; 4.2.6 Absorption Through Various Sites; 4.3 Distribution of Drugs; 4.3.1 Blood Flow; 4.3.2 Capillary Permeability; 4.3.3 Binding of Drugs to Proteins; 4.3.4 Volume of Distribution; 4.4 Drug Metabolism; 4.4.1 Phase l Reactions; 4.4.2 Phase ll Reactions; 4.4.3 Factors Affecting Drug Metabolism; 4.4.4 Genetic Polymorphisms; 4.4.5 Metabolism and Drug Toxicity; 4.5 Drug Elimination; 4.5.1 Renal Elimination of a Drug; Chapter 5. Combined Effect of Drugs; 5.1 Introduction; 5.2 Addition or Summation.
5.3 Potentiation or Synergism5.4 Antagonism; 5.4.1 Chemical Antagonism; 5.4.2 Physiologic Antagonism; 5.4.3 Receptor Block Antagonism; Chapter 6. Mechanisms of Action of Drugs; 6.1 Introduction; 6.2 Terminology; 6.3 Basis of Drug Action; 6.3.1 Receptors; 6.3.2 Ion Channels; 6.3.3 Enzymes; 6.3.4 Carrier Molecules; 6.4 Second Messengers; 6.4.1 Modulation of Receptor Effect via the Intracellular Second Messenger and/or G-Proteins; 6.5 Desensitization of Receptors; 6.6 Therapeutic Index; 6.6.1 Evaluation of Therapeutic Index; Chapter 7. Bioavailability of Drugs; 7.1 Introduction.
7.2 Bioavailability and Various Determinants7.2.1 Determination of Bioavailability; 7.2.2 Single Dose Bioavailability; 7.2.3 Multiple Dose Bioavailability; 7.2.4 Guiding Factors for Bioavailability; 7.2.5 Importance of Bioavailability; 7.2.6 Bioequivalence; 7.2.7 Therapeutic Equivalence; 7.2.8 Biological Half-Life; Chapter 8. Factors Modifying Drug Action; 8.1 Introduction; 8.2 Factors Influencing Drug Response; 8.2.1 Age and Body Weight; 8.2.2 Sex; 8.2.3 Biological Variation; 8.2.4 Pharmacogenetic Factors; 8.2.5 Routes and Method of Administration; 8.2.6 Physiological Factors.
Edition Notes
8.2.7 Psychological States.
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