Dr. Henry Moss has long been seeking a cure for a congenital disease in children, called Hickman, that causes them to age rapidly and die before their teens. A thoughtful and dedicated man, Henry wants only to give his small, wizened patients their share of the bounteous future promised by this prosperous moment in dot-com Seattle. To his amazement, his study takes a remarkable turn: he is consulted by a family whose three-year-old son, Giles, is clearly stricken with Hickman. Giles's teenage brother also tests positive for the disease -- but he displays no symptoms. In fact, all the aging mechanisms in his body seem to have halted. This discovery is a potential goldmine. It is also a minefield of personal and medical ethics.

All around Henry, the world beckons with easy comfort and instant wealth. The temptation to fulfill his own family's longings is powerful. Henry's wife, trained as a doctor in her native Vienna, languishes in a dead-end job. Their two teenage children endure the pangs of adolescent yearning: Sandra, star of her basketball team, is in love with her sport and also with the wrong boy; Darren, at fourteen, drifts, hapless and unmoored.