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"RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development provides a general overview of this rapidly emerging field, with a strong emphasis on issues and aspects that are important to a drug development team. The first part covers more general background of RNA interference and its application in drug discovery. In the second part, the book addresses siRNA (small interfering RNA), a pharmaceutically potent form, and its use and delivery in therapeutics along with manufacturing and delivery aspects"--Provided by publisher.
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Previews available in: English
Edition | Availability |
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RNA interference: application to drug discovery and challenges to pharmaceutical development
2011, Wiley
in English
0471771511 9780471771517
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Book Details
Table of Contents
(Publisher-supplied data) RNA interference: What is it? / James A. Birchler
Nucleic acids as regulatory molecules / Faqing Huang, CJ Yu, and Yanlin Guo
Use of siRNA oligonucleotides to study gene function / Kristin A. Wiederholt and Adam N. Harris
Genome scanning by RNA interference / Roderick L. Beijersbergen and Oliver C. Steinbach
Discovery of new siRNA delivery agents / Paul H. Johnson, Diane Frank, Kunyuan Cui, Roger Adami, Harry Wang, Michael Houston, and Steven C. Quay
In vivo Delivery of siRNA: challenges and strategies / Aliasger K. Salem and Mark A. Behlke
Interferon, cytokine induction and other potential in vivo toxicities / Adam Judge, Marjorie Robbins, and Ian MacLachlan
Application of RNA interference to viral diseases / Ralph A. Tripp and Stephen Mark Tompkins.
Edition Notes
Includes bibliographical references and index.
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Feedback?August 2, 2020 | Edited by ImportBot | import existing book |
December 9, 2010 | Created by ImportBot | initial import |