An edition of G protein-coupled receptors in drug discovery
(2009)
G protein-coupled receptors in drug discovery
by Wayne R. Leifert
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Previews available in: English
Subjects
Recherche, Drug development, Receptors, Screening, Untersuchungsmethode, Wirkstoff, Arzneimittelforschung, Laboratory Manuals, Protéines G, Pharmacie, Récepteurs, Receptors, G-Protein-Coupled, G-Proteine, G proteins, Drug Discovery, Rezeptor, Proteins, Pharmacology, Drug receptors, Drug delivery systems, Drugs, design| Edition | Availability |
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1
G Protein-Coupled Receptors in Drug Discovery
2016, Humana Press
in English
1493957066 9781493957064
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2
G protein-coupled receptors in drug discovery
2009, Humana Press
in English
1603273166 9781603273169
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Book Details
Table of Contents
New insights into GPCR function: implications for HTS -- R.M. Eglen and T. Reisine
Screening technologies for G protein-coupled receptors: from HTS to uHTS -- M. De los Frailes and E. Diez
GPCR signaling: understanding the pathway to successful drug discovery -- C. Williams and S.J. Hill
An overview on GPCRs and drug discovery: structure-based drug design and structural biology on GPCRs -- K. Lundstrom
Understanding the ligand-receptor-G protein ternary complex for GPCR drug discovery -- V.R. Ratnala and B. Kobilka
Assay data quality assessment -- H. Gubler
Homology modeling of GPCRs -- J. Simms ... [et al.]
GPCR expression using baculovirus-infected Sf9 cells -- A.L. Aloia ... [et al.]
Radioligand binding assays: application of [(125)I]angiotensin II receptor binding -- W.R. Leifert ... [et al.]
[35S]GTPgammaS binding in G protein-coupled receptor assays -- T. Cooper, E.J. McMurchie and W.R. Leifert
A time-resolved fluorescent lanthanide (Eu)-GTP binding assay for chemokine receptors as targets in drug discovery -- J. Labrecque, R.S. Wong and S.P. Fricker
Use of the DiscoveRx Hit hunter cAMPII assay for direct measurement of cAMP in Gs and Gi GPCRs -- J. Bradley and D. McLoughlin
Use of aequorin for G protein-coupled receptor hit identification and compound profiling -- S.J. Brough and P. Shah
BacMam: versatile gene delivery technology for GPCR assays -- E.A. Davenport, P. Nuthulaganti and R.S. Ames
Yeast assays for G protein-coupled receptors -- S.J. Dowell and A.J. Brown
GPCR microspot assays on solid substrates -- Y. Fang and J. Lahiri
Resonant waveguide grating biosensor for whole-cell GPCR assays -- Y. Fang, A.M. Ferrie and E. Tran
FRET-based measurement of GPCR conformational changes -- S. Granier ... [et al.]
FLIPR assays of intracellular calcium in GPCR drug discovery -- K.B. Hansen and H. Brauner-Osborne
Use of fluorescence indicators in receptor ligands -- K.G. Harikumar and L.J. Miller
Application of fluorescence resonance energy transfer techniques to establish ligand-receptor orientation -- K.G. Harikumar and L.J. Miller
Detection of GPCR/beta-arrestin interactions in live cells using bioluminescence resonance energy transfer technology -- M. Kocan and K.D. Pfleger
Using reporter gene technologies to detect changes in cAMP as a result of GPCR activation -- D.J. Rodrigues and D. McLoughlin
A quantum dot-labeled ligand-receptor binding assay for G protein-coupled receptors contained in minimally purified membrane nanopatches -- J.L. Swift, M.C. Burger and D.T. Cramb
Xenopus oocyte electrophysiology in GPCR drug discovery -- K.B. Hansen and H. Brauner-Osborne
Immunoprecipitation and phosphorylation of G protein-coupled receptors -- W.G. Thomas.
Edition Notes
Includes bibliographical references and index.
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| February 26, 2022 | Edited by ImportBot | import existing book |
| June 30, 2019 | Edited by MARC Bot | import existing book |
| July 23, 2011 | Created by LC Bot | import new book |