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"Therapeutic applications of quadruplex nucleic acids provides a single comprehensive survey that describes and assesses recent advances in quadruplex therapeutics and targeting strategies. It also covers the underlying fundamentals of such topics as quadruplex structure, small-molecule recognition, biological roles of genomic quadruplexes, and quadruplex informatics"--P. [4] of cover.
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Edition | Availability |
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Therapeutic applications of quadruplex nucleic acids
2012, Elsevier/Academic Press
in English
- 1st ed.
0123751381 9780123751386
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Book Details
Table of Contents
Introduction: quadruplexes and their biology
DNA and RNA quadruplex structures
The structures of human telomeric DNA quadruplexes
Telomeric quadruplex ligands I: anthraquinones and acridines
Telomeric quadruplex ligands II: polycyclic and non-fused ring compounds
The biology and pharmacology of telomeric quadruplex ligands
Genomic quadruplexes as therapeutic targets
RNA quadruplexes
Design principles for quadruplex-binding small molecules
The determination of quadruplex structures.
Edition Notes
Includes bibliographical references and index.
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