Proteinnanoparticle Interactions The Bionano Interface

Locate

My Reading Lists:

Create a new list

Check-In

×Close
Add an optional check-in date. Check-in dates are used to track yearly reading goals.
Today


Buy this book

Last edited by MARC Bot
September 16, 2024 | History

Proteinnanoparticle Interactions The Bionano Interface

In recent years, the fabrication of nanomaterials and exploration of their properties have attracted the attention of various scientific disciplines such as biology, physics, chemistry, and engineering. Although nanoparticulate systems are of significant interest in various scientific and technological areas, there is little known about the safety of these nanoscale objects. It has now been established that the surfaces of nanoparticles are immediately covered by biomolecules (e.g. proteins, ions, and enzymes) upon their entrance into a biological medium. This interaction with the biological medium modulates the surface of the nanoparticles, conferring a “biological identity” to their surfaces (referred to as a “corona”), which determines the subsequent cellular/tissue responses. The new interface between the nanoparticles and the biological medium/proteins, called “bio-nano interface,” has been very rarely studied in detail to date, though the interest in this topic is rapidly growing. In this book, the importance of the physiochemical characteristics of nanoparticles for the properties of the protein corona is discussed in detail, followed by comprehensive descriptions of the methods for assessing the protein-nanoparticle interactions. The advantages and limitations of available corona evaluation methods (e.g. spectroscopy methods, mass spectrometry, nuclear magnetic resonance, electron microscopy, X-ray crystallography, and differential centrifugal sedimentation) are examined in detail, followed by a discussion of the possibilities for enhancing the current methods and a call for new techniques. Moreover, the advantages and disadvantages of protein-nanoparticle interaction phenomena are explored and discussed, with a focus on the biological impacts.

Publish Date
Pages
84

Buy this book

Edition Availability
Cover of: Proteinnanoparticle Interactions The Bionano Interface
Proteinnanoparticle Interactions The Bionano Interface
2013, Springer-Verlag Berlin and Heidelberg GmbH &

Add another edition?

Book Details


Classifications

Library of Congress
T174.7 .R34 2013, QH301-705, QH345, QD415-436

ID Numbers

Open Library
OL26013051M
ISBN 13
9783642375545
LCCN
2013941547

Community Reviews (0)

Feedback?
No community reviews have been submitted for this work.

Lists

This work does not appear on any lists.

History

Download catalog record: RDF / JSON
September 16, 2024 Edited by MARC Bot import existing book
October 5, 2021 Edited by ImportBot import existing book
November 12, 2020 Edited by MARC Bot import existing book
October 14, 2016 Edited by Mek Added new cover
October 14, 2016 Created by Mek Added new book.