An edition of BACE (2010)

BACE

lead target for orchestrated therapy of Alzheimer's disease

by

Cover of: BACE by Varghese John
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Last edited by ImportBot
October 9, 2020 | History
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An edition of BACE (2010)

BACE

lead target for orchestrated therapy of Alzheimer's disease

by

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Publish Date
Publisher
John Wiley & Sons
Language
English

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Previews available in: English

Subjects

Alzheimer Disease, Pharmacology, Aspartic proteinases, Inhibitors, Amyloid beta-protein precursor, Drug therapy, Chemotherapy, Therapeutic use, Alzheimer's disease, Amyloid Precursor Protein Secretases, Proteinase, Proteins
Edition Availability
Cover of: BACE
BACE: lead target for orchestrated therapy of Alzheimer's disease
2010, John Wiley & Sons
in English
Cover of: Bace
Bace
2010, Wiley & Sons, Incorporated, John
in English
Cover of: Bace
Bace: Lead Target for Orchestrated Therapy of Alzheimer's Disease
2010, Wiley & Sons, Incorporated, John
in English

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Book Details

Table of Contents

BACE : APP processing, and signal transduction in Alzheimer's disease (AD) / Dale E. Bredesen and Edward H. Koo
Identification of BACE as an AD target / Robert L. Heinrikson and Sukanto Sinha
BACE biological assays / Alfredo G. Tomasselli and Michael J. Bienkowski
Peptidic, peptidomimetic, and HTS based BACE inhibitors / James P. Beck and Dustin J. Mergott
Fragment-based approaches for identification of BACE inhibitors / Andreas Kuglstatter and Michael Hennig
Structure-based drug design of BACE inhibitors : technical and practical aspects of preparation, 3-dimensional structure, and computational analysis / Felix F. Vajdos, Veer Shanmugasundaram, and Alfredo G. Tomasselli
Pharmacological models for preclinical testing : from mouse to dog to non-human primates / Jason L. Eriksen, Michael Paul Murphy, and Elizabeth Head
Adsorption, distribution, metabolism, excretion (ADME), efficacy & toxicology for BACE inhibitors / Ishrut Hussain and Emmanuel Demont
Clinical trials for disease modifying drugs such as BACE inhibitors / Henry Hsu
Future strategies for development of novel BACE inhibitors : anti-APP e-site antibody & APP binding small molecule approaches for Alzheimer's disease / Beka Solomon ... [et al.].

Edition Notes

Includes bibliographical references and index.

Published in
Hoboken, N.J

Classifications

Dewey Decimal Class
618.97/6831
Library of Congress
RC523 .B24 2010, RC523.B24 2010

The Physical Object

Pagination
p. ;

ID Numbers

Open Library
OL23735687M
Internet Archive
baceleadtargetfo00john_740
ISBN 13
9780470293423
LCCN
2009037093

Source records

Library of Congress MARC record
Internet Archive item record
Internet Archive item record
Better World Books record
Library of Congress MARC record

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October 9, 2020 Edited by ImportBot import existing book
August 1, 2020 Edited by ImportBot import existing book
June 28, 2019 Edited by MARC Bot import existing book
February 5, 2019 Created by MARC Bot import existing book